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Phase 1
Age: 8Years - 21Years
All Genders
ID05154253

Augmenting Ankle Plantarflexor Function and Walking Capacity in Children With Cerebral Palsy

Led by Northern Arizona University · Updated on 2026-03-03

36

Participants Needed

1

Research Sites

1 weeks

Total Duration

On this page

Sponsors

N

Northern Arizona University

Lead Sponsor

G

Gillette Children's Specialty Healthcare

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to improve walking ability and muscle function in children with cerebral palsy CP, a common cause of physical disability in children. The study focuses on addressing plantarflexor dysfunction, which contributes to slow and inefficient walking patterns in CP. Researchers are evaluating a wearable robotic device that provides targeted ankle resistance for neuromuscular training and adaptive ankle assistance to support walking during challenging tasks. The study includes two main approaches. First, it compares targeted ankle resistance training twice a week for 12 weeks against standard physical therapy and standard treadmill training to see which produces better improvements in muscle control, gait, and mobility. Second, it assesses adaptive ankle assistance compared to standard ankle foot orthoses and walking without any device during walking tests, treadmill exercises, and stair stepping to measure walking capacity and performance. Participants will attend multiple sessions involving different types of gait training and assistive device use. Researchers will measure changes in walking speed, muscle activity, stride length, posture, strength, and performance on walking tests immediately after the intervention, then again at 2 and 12 weeks later. Other assessments include metabolic cost, heart rate, and exertion during walking tasks. The total duration of involvement varies with repeated measures and follow-up evaluations to monitor progress and safety.

CONDITIONS

Brief Title

Augmenting Ankle Plantarflexor Function in Cerebral Palsy

Who Can Participate

Age: 8Years - 21Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ages between 8 and 21 years old, inclusive, with a diagnosis of cerebral palsy and ankle-related walking difficulties.
  • Ability to understand and follow simple directions and walk at least 30 feet with or without a walking aid.
  • At least 20 degrees of passive ankle plantar-flexion range of motion.
Not Eligible

You will not qualify if you...

  • Receiving any treatment other than those assigned during the study.
  • Having a condition other than cerebral palsy that would affect safe participation.
  • Undergoing surgical intervention within 6 months before participation.

Research Team

Z

Zach Lerner, PhD

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