Actively Recruiting

Phase 1
Age: 8Years - 21Years
All Genders
NCT05154253

Augmenting Ankle Plantarflexor Function in Cerebral Palsy

Led by Northern Arizona University · Updated on 2026-03-03

36

Participants Needed

1

Research Sites

190 weeks

Total Duration

On this page

Sponsors

N

Northern Arizona University

Lead Sponsor

G

Gillette Children's Specialty Healthcare

Collaborating Sponsor

AI-Summary

What this Trial Is About

The first specific aim is to quantify improvement in ankle muscle function and functional mobility following targeted ankle resistance gait training in ambulatory children with cerebral palsy (CP). The primary hypothesis for the first aim is that targeted ankle resistance training will produce larger improvements in lower-extremity motor control, gait mechanics, and clinical measures of mobility assessed four- and twelve-weeks post intervention compared to standard physical therapy and standard gait training. The second specific aim is to determine the efficacy of adaptive ankle assistance to improve capacity and performance during sustained, high-intensity, and challenging tasks in ambulatory children with CP. The primary hypothesis for the second aim is that adaptive ankle assistance will result in significantly greater capacity and performance during the six-minute-walk-test and graded treadmill and stair stepping protocols compared to walking with ankle foot orthoses and walking with just shoes.

CONDITIONS

Official Title

Augmenting Ankle Plantarflexor Function in Cerebral Palsy

Who Can Participate

Age: 8Years - 21Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 8 and 21 years old, inclusive
  • Diagnosis of cerebral palsy with a gait pattern caused by ankle dysfunction
  • Able to understand and follow simple directions
  • Able to walk at least 30 feet with or without a walking aid (GMFCS Level I-III)
  • At least 20 degrees of passive plantar-flexion range of motion
Not Eligible

You will not qualify if you...

  • Receiving treatment other than those assigned during the study
  • Having a condition other than cerebral palsy that affects safe participation
  • Underwent surgical intervention within 6 months before participation

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Gillette Children's Specialty Healthcare

Minneapolis, Minnesota, United States, 55101

Actively Recruiting

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Research Team

Z

Zach Lerner, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

6

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