Actively Recruiting
Augmenting Massed Cognitive Processing Therapy (CPT) to Prevent Suicide Risk Among Patients With PTSD
Led by Ohio State University · Updated on 2026-02-24
190
Participants Needed
1
Research Sites
43 weeks
Total Duration
On this page
Sponsors
O
Ohio State University
Lead Sponsor
U
University of Vermont Medical Center
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research aims to find out if adding Crisis Response Planning (CRP), a brief strategy to help manage emotional crises, to massed Cognitive Processing Therapy (CPT), a talk therapy for posttraumatic stress disorder (PTSD), can better reduce suicidal thoughts and behaviors. The study focuses on military personnel and veterans with PTSD or subthreshold PTSD who have experienced recent suicidal ideation or attempts. It builds on earlier findings suggesting that combining CRP with CPT may improve outcomes for those facing both PTSD symptoms and suicide risk. Participants will be randomly assigned to one of two groups: one receiving massed CPT plus CRP, and the other receiving massed CPT plus usual care suicide risk management, which involves a standard safety planning procedure. All participants will attend 10 daily CPT sessions over two consecutive weeks. The suicide risk intervention, whether CRP or usual care, is introduced during the intake session and reviewed during treatment. Optional booster sessions are also available. Throughout the study, participants will complete baseline assessments, daily therapy sessions, and ecological momentary assessment (EMA) surveys for four weeks. Follow-up assessments will occur at 1, 3, 6, 9, and 12 months after treatment. Researchers will monitor PTSD symptoms using the PTSD Checklist for DSM-5 and track suicidal thoughts and behaviors with several interviews and scales. The study aims to identify early indicators of treatment response and understand which parts of CRP are most helpful to participants. Safety and progress will be carefully observed during and after the study period.
CONDITIONS
Brief Title
Augmenting Massed Cognitive Processing Therapy (CPT) to Prevent Suicide Risk Among Patients With PTSD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Active duty service member or veteran aged 18 or older eligible for military medical care
- Able to read, write, and speak English
- Meet criteria for PTSD or subthreshold PTSD on the Clinician Administered PTSD Scale for DSM-5 (CAPS-5)
- Have active suicidal ideation within the past week or a suicide attempt within the past month
- Regular use of an iPhone or Android smartphone
You will not qualify if you...
- Unable to understand or complete consent and baseline questionnaires
- Current suicide or homicide risk requiring crisis intervention
- Serious mental health symptoms such as mania, psychosis, or substance use disorders needing immediate attention
- Currently receiving evidence-based psychotherapy for PTSD such as Cognitive Processing Therapy, Prolonged Exposure Therapy, or Written Exposure Therapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
screening and enrollment visit
Duration - 2 weeks
Participants receive 10 daily sessions of Cognitive Processing Therapy (CPT) over two consecutive weeks, combined with either Crisis Response Planning (CRP) or usual care safety planning to manage suicide risk.
10 daily visits (in-person) Monday through Friday over two consecutive weeks
Duration - 4 weeks
Participants complete ecological momentary assessment (EMA) surveys for four weeks to monitor symptoms and suicidal thoughts during and after treatment.
daily EMA surveys
Duration - 12 months
Participants attend follow-up assessments to evaluate PTSD symptoms and suicidal thoughts at 1, 3, 6, 9, and 12 months after treatment completion.
5 follow-up visits at 1, 3, 6, 9, and 12 months
Trial Site Locations
Total: 1 location
1
Carl R. Darnall Army Medical Center
Fort Hood, Texas, United States, 76544-9800
Actively Recruiting
Research Team
C
C. Rosie Bauder, PhD, MPH
A
Anna Crouser, MSW
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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