Study on Improving Outcomes for Adults With Critical Bleeding Who Need Massive Transfusion

What this Trial Is About

Researchers are gathering detailed information about patients who have experienced severe bleeding that required a massive transfusion, such as after serious injury, surgery, or childbirth. This observational study collects and analyzes data to better understand how often these events occur, what happens to patients, and how blood transfusions are used in these situations. The study is conducted by Monash University and includes data from multiple hospitals in Australia and New Zealand. The study uses electronic methods to collect existing clinical data from hospital databases, including transfusion records and patient demographics. This information is securely linked and analyzed to provide insights into transfusion practices and patient outcomes after critical bleeding events. The registry includes data from over 6,000 patients across 25 sites, covering various clinical settings such as trauma, surgery, obstetrics, and gastrointestinal bleeding. Participants in this study are adults who experienced critical bleeding and received at least five units of red blood cells within four hours. The study monitors outcomes such as mortality within 30 days after the bleeding event. Data linkage with national death indexes and other registries helps provide comprehensive outcome measurements. The study allows ongoing collection and analysis of data to improve transfusion policies and patient care practices over time.

Australian and New Zealand Massive Transfusion Registry