Actively Recruiting

Phase 2
Age: 0 - 75Years
All Genders
NCT03125642

Auto Stem Cell Transplant for Lymphoma Patients

Led by Masonic Cancer Center, University of Minnesota · Updated on 2025-11-04

150

Participants Needed

1

Research Sites

523 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a phase II study of autologous transplant for patients with Hodgkin (HL) and non-Hodgkin lymphomas (NHL) including those who are HIV positive.

CONDITIONS

Official Title

Auto Stem Cell Transplant for Lymphoma Patients

Who Can Participate

Age: 0 - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of chemo-sensitive non-Hodgkin lymphoma (NHL) or Hodgkin lymphoma (HL) confirmed by histology
  • NHL patients in partial or complete remission after cell therapy
  • Specific lymphoma subtypes with defined remission or risk status as detailed in protocol
  • HIV positive patients under active HIV care with controlled viral load and CD4+ count 6/bcl
  • Karnofsky Performance Status 80% (or Lansky Play Score 80 for patients under 16 years)
  • Adequate organ function including hematologic, renal, hepatic, cardiac, pulmonary, and CNS criteria
  • At least 4 weeks since last chemotherapy (6 weeks for nitrosoureas)
  • Agreement to use birth control for women of childbearing potential and sexually active males
  • Voluntary written consent
Not Eligible

You will not qualify if you...

  • Pregnancy or breastfeeding
  • Eligibility for higher priority transplant protocols
  • Chemotherapy resistant disease (no partial response after up to 3 chemotherapy cycles)
  • Active unrelated infections
  • Serious uncontrolled organ dysfunction not related to lymphoma

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Masonic Cancer Center, University of Minnesota

Minneapolis, Minnesota, United States, 55455

Actively Recruiting

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Research Team

T

Timothy Krepski

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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