Actively Recruiting

Age: 18Years +
All Genders
NCT06334692

Autoantibodies Against-nephrin in Idiopathic Nephrotic Syndrome

Led by Mario Negri Institute for Pharmacological Research · Updated on 2025-09-04

100

Participants Needed

1

Research Sites

206 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This retrospective study is aimed at evaluating the levels of circulating anti-nephrin autoantibodies in patients with INS, including those with MCD/FSGS and in patients who have experienced relapse of FSGS post-transplant, compared to those of a control group of patients with nephrotic syndrome due to primary membranous nephropathy (MN).

CONDITIONS

Official Title

Autoantibodies Against-nephrin in Idiopathic Nephrotic Syndrome

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults older than 18 years
  • Patients with biopsy-confirmed idiopathic minimal change disease or focal segmental glomerulosclerosis
  • Patients with biopsy-confirmed idiopathic membranous nephropathy
  • Patients who consented to store their samples in the certified biobank
Not Eligible

You will not qualify if you...

  • Possible secondary cause of nephrotic syndrome or membranous nephropathy at the time of blood collection
  • Active viral or bacterial infections at the time of blood collection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Clinical Research Center for Rare Disease Aldo e Cele Daccò

Ranica, BG, Italy, 24020

Actively Recruiting

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Research Team

F

Federica Casiraghi, PhD

CONTACT

N

Norberto Perico, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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