Actively Recruiting
Autogenous Tooth Transplantation With Instrumentally Simulated Open Apex and Platelet-Rich Fibrin
Led by University of Bari Aldo Moro · Updated on 2026-02-06
5
Participants Needed
1
Research Sites
34 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Autogenous tooth transplantation (autotransplantation) represents a biologically valid alternative to implant therapy, particularly in young patients where implant placement is contraindicated due to ongoing skeletal growth. This approach preserves alveolar bone volume, maintains periodontal proprioception, and allows physiological adaptation over time.
CONDITIONS
Official Title
Autogenous Tooth Transplantation With Instrumentally Simulated Open Apex and Platelet-Rich Fibrin
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Early loss of permanent teeth due to trauma, extensive caries, or agenesis
- Dental agenesis involving premolars or incisors with a suitable donor tooth
- Replacement of non-restorable teeth such as fractures or destructive caries
- Preservation of alveolar bone in growing patients where implants are contraindicated
- Functional and aesthetic rehabilitation of anterior teeth in children and adolescents
- Post-traumatic oral rehabilitation in young patients
- Good general and oral health
- Presence of vital and intact periodontal ligament on the donor tooth
- Adequate or surgically adaptable recipient site dimensions and morphology
- Absence of active infection at the recipient site
- Donor tooth extracted for orthodontic reasons, impacted or erupting third molars with compatible shape, or suitable supernumerary teeth
You will not qualify if you...
- Poor patient compliance
- Active infection at the recipient site
- Smoking more than 15 cigarettes a day
- Untreated periodontal disease
- Pregnancy or breastfeeding at the time of inclusion
- Acute infections
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Bari Aldo Moro, Hospital
Bari, Italy, 70124
Actively Recruiting
Research Team
G
Giuseppe D'Albis, Dr.
CONTACT
N
Nicola De Giglio, Dr.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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