Actively Recruiting
Autoimmune Disease Treatment With Mesenchymal Stem Cells (MSCs) and CAR-T Cells
Led by Shenzhen Geno-Immune Medical Institute · Updated on 2026-04-24
30
Participants Needed
1
Research Sites
189 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to assess the feasibility, safety and efficacy of mesenchymal stem cells (MSCs) in combination with CAR-T cells in treating autoimmune disease. Another goal of the study is to learn more about the safety and function of the MSCs combined with CAR-T cells and their long term effects in autoimmune disease patients.
CONDITIONS
Official Title
Autoimmune Disease Treatment With Mesenchymal Stem Cells (MSCs) and CAR-T Cells
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Older than 18 years of age
- Diagnosed with autoimmune conditions
- Karnofsky Performance Status (KPS) score over 80 points
- Expected survival time of more than 3 months
- Hemoglobin level greater than 80 g/L
- No contraindications to blood cell collection
You will not qualify if you...
- Having other active diseases making it difficult to assess treatment response
- Uncontrolled bacterial, fungal, or viral infections
- Living with HIV
- Active hepatitis B virus (HBV) or hepatitis C virus (HCV) infection
- Pregnant or nursing mothers
- Systemic steroid treatment within one week before treatment
- Previous CAR-T treatment that failed
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shenzhen Geno-immune Medical Institute
Shenzhen, Guangdong, China, 518000
Actively Recruiting
Research Team
L
Lung-Ji Chang, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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