Actively Recruiting
Autologous and Allogeneic Whole Cell Cancer Vaccine for Metastatic Tumors
Led by Hadassah Medical Organization · Updated on 2025-10-02
50
Participants Needed
1
Research Sites
965 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is based on the finding that tumor cells that are grown in the laboratory can be modified in such a way that, when injected to the patient, they will stimulate his/her immune response. This approach will be evaluated in patients with melanoma and colorectal, gastric, ovarian, breast, lung and kidney epithelial cancer. Tumor cells grown in the laboratory will be modified to make them stimulatory to the immune system, irradiated to kill them, and injected to the patient eight times at two-week intervals. This protocol is expected to prolong survival of metastatic cancer patients.
CONDITIONS
Official Title
Autologous and Allogeneic Whole Cell Cancer Vaccine for Metastatic Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have metastatic melanoma, breast, ovary, colorectal, gastric, lung, or kidney cancer
- Are 18 years of age or older
- Have failed at least one chemotherapy protocol
- Have an ECOG performance status of 0 or 1
- Have an absolute neutrophil count greater than 1000/mm3
- Have serum ALT and AST levels less than three times the upper limit of normal
- Have serum creatinine less than or equal to 1.6 mg/dl
- Are able to understand and sign the informed consent document
You will not qualify if you...
- Are under 18 years of age
- Are pregnant
- Have a life expectancy of less than three months
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Hadassah Medical Organization
Jerusalem, Israel, 91120
Actively Recruiting
Research Team
H
Hani Steinberg, R.N. B.A.
CONTACT
T
Tamar Peretz, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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