Actively Recruiting
Autologous Costal Osteochondral Transplantation for Talar Osteochondral Lesions
Led by The Third Affiliated Hospital of Southern Medical University · Updated on 2023-09-06
50
Participants Needed
1
Research Sites
230 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to evaluate the effectiveness and safety of autologous costal osteochondral transplantation in the treatment of Hepple Stage V talar osteochondral lesions, compared with autologous osteoperiosteal transplantation. The main question it aims to answer is: • Whether autologous costal osteochondral transplantation can achieve better clinical outcomes and cartilage repair quality with lower donor site morbidity than autologous osteoperiosteal transplantation in the treatment of Hepple Stage V talar osteochondral lesions. Participants will be randomly assigned to the intervention group (undergoing autologous costal osteochondral transplantation) or the control group (undergoing autologous osteoperiosteal transplantation). Both groups of participants will receive the same postoperative rehabilitation process and follow-up evaluation.
CONDITIONS
Official Title
Autologous Costal Osteochondral Transplantation for Talar Osteochondral Lesions
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Symptomatic Hepple stage V talar osteochondral lesions with lesion depth 25 5 mm and AOFAS score 25 80 points
- Failed conservative treatment for at least 6 months
- Unilateral talar osteochondral lesions without corresponding tibial lesions
- Willingness to participate and signing informed consent form
You will not qualify if you...
- Presence of lower limb deformity
- Presence of hip or knee joint diseases
- Ipsilateral ankle arthritis with joint space narrowing
- Diagnosis of gouty arthritis of the ankle joint
- Osteoporosis with T score < -2.5
- Other conditions deemed inappropriate by researchers
AI-Screening
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Trial Site Locations
Total: 1 location
1
The Third Affiliated Hospital of Southern Medical University
Guangzhou, Guangdong, China, 510630
Actively Recruiting
Research Team
H
Hao Guo, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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