Actively Recruiting
Autologous Mesenchymal Stromal Cells and Islet Co-transplantation in TP-IAT
Led by Medical University of South Carolina · Updated on 2026-04-16
42
Participants Needed
1
Research Sites
291 weeks
Total Duration
On this page
Sponsors
M
Medical University of South Carolina
Lead Sponsor
N
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a clinical trial for chronic pancreatitis (CP) patients undergoing total pancreatectomy with islet autotransplantation (TP-IAT). Participants will be randomized to either bone marrow-derived mesenchymal stem cells (MSCs) or control with the standard of care. Participants will be followed for one-year post-transplant.
CONDITIONS
Official Title
Autologous Mesenchymal Stromal Cells and Islet Co-transplantation in TP-IAT
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of chronic pancreatitis and scheduled for total pancreatectomy with islet autotransplantation
- 18 years of age or older
- Diabetes with HbA1c less than 12%
You will not qualify if you...
- Currently taking immunosuppressive medications
- Pregnant or breastfeeding women
- Liver damage indicated by ALT, AST, or total bilirubin levels more than 3 times the normal range
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
Actively Recruiting
Research Team
L
Leah Benn, MPH
CONTACT
K
Kelsey Cook
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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