Actively Recruiting
Autologous Non-cultured Epidermal Cell Suspension Transplantation in the Treatment of Vitiligo
Led by Peking University People's Hospital · Updated on 2025-09-23
30
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the long-term effectiveness and safety of a treatment called autologous non-cultured epidermal cell suspension transplantation for people with vitiligo. This study aims to understand how cell density and type relate to treatment results and prognosis, providing useful information for clinical use. Participants include those with stable segmental, unclassified, or non-segmental vitiligo that has not responded to medications or light therapy. The treatment involves taking thin skin grafts from the thigh and preparing a cell suspension using a specialized kit. The skin area affected by vitiligo is then carefully dermabraded until small bleeding points appear. This cell suspension is applied to the treated skin, which is then covered with layers of dressings and elastic bandages for 10 days. After removal of dressings, patients are monitored closely over several months. Participants will visit the hospital for follow-up checks at 2 weeks, then monthly up to 6 months after the procedure. During these visits, the degree of skin repigmentation will be assessed and rated from poor to excellent. Skin color changes will be measured using specialized devices, and laboratory tests will analyze cell numbers, vitality, and types in the suspension. This extensive monitoring helps researchers measure outcomes and safety throughout the study period.
CONDITIONS
Brief Title
Autologous Non-cultured Epidermal Cell Suspension Transplantation in the Treatment of Vitiligo
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with vitiligo according to the 2021 Vitiligo Diagnosis and Treatment Consensus
- Segmental and unclassified vitiligo stable for at least 6 months, or non-segmental vitiligo stable for at least 1 year and resistant to medication and phototherapy
- Body surface area affected is 5% or more
- Willing to sign informed consent and undergo surgical treatment
- Age between 8 and 65 years, any gender
You will not qualify if you...
- Severe organ or infectious disease that makes surgery unsafe
- Tendency to develop keloid scars
- Blood clotting problems
- Unable to complete scheduled follow-up visits on time
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 10 days
Participants undergo autologous non-cultured epidermal cell suspension transplantation involving skin graft collection, preparation of cell suspension, dermabrasion of the recipient site, application of the cell suspension, and wound dressing which is removed 10 days after transplantation.
1 surgical visit and dressing removal visit
Duration - 6 months
Participants return for follow-up examinations to assess repigmentation and skin indices after transplantation.
7 visits at 2 weeks, 1 month, 2 months, 3 months, 4 months, 5 months, and 6 months post-transplantation
Trial Site Locations
Total: 1 location
1
Peking University People's Hospital
Beijing, Beijing Municipality, China, 100044
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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