Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
FEMALE
NCT03496636

Autologous Ovarian Tissue Transplantation

Led by University of Pittsburgh · Updated on 2025-08-14

5

Participants Needed

1

Research Sites

339 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Chemotherapy and radiation for cancer and other conditions can cause infertility. Several centers around the world are cryopreserving ovarian tissue from these patients though an experimental protocol, including the Fertility Preservation Program in Pittsburgh (protocol PRO08050491). The objective of this study is to study the efficacy and safety of autologous tissue transplantation in patients diagnosed with primary ovarian insufficiency after chemotherapy and/or radiation treatments.

CONDITIONS

Official Title

Autologous Ovarian Tissue Transplantation

Who Can Participate

Age: 18Years - 45Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Previously cryopreserved ovarian tissue
  • Diagnosis of ovarian insufficiency and/or being a candidate for pregnancy
  • Good general health
  • Clearance from oncologist to participate
Not Eligible

You will not qualify if you...

  • High risk for surgical complications
  • Contraindications to pregnancy if pregnancy is a study goal
  • Positive for BRCA mutations
  • History of leukemia, ovarian cancer, or cancers likely involving ovaries when tissue was collected
  • Psychological or psychiatric conditions preventing informed consent
  • Current pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Magee-Womens Hospital

Pittsburgh, Pennsylvania, United States, 15213

Actively Recruiting

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Research Team

J

Jennifer Anglin

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Autologous Ovarian Tissue Transplantation | DecenTrialz