Actively Recruiting
Autologous SVF Therapy for Type 2 Diabetes
Led by Kaiser Clinic and Hospital · Updated on 2026-03-23
10
Participants Needed
1
Research Sites
101 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This prospective clinical study aims to evaluate the safety and efficacy of autologous adipose-derived stromal vascular fraction (SVF), enriched with mesenchymal stem cells (ADSCs), for the treatment of Type 2 Diabetes Mellitus (T2DM). Adipose tissue will be harvested using a 1210-nm diode laser-assisted selective photochemical stimulation technique (One-STEP™ method), followed by centrifugation without enzymatic digestion. The isolated SVF will be injected endoluminally into the duodenal submucosa during the same surgical procedure. Five adult patients with T2DM will be followed for six months to assess metabolic control, pancreatic function, and quality of life outcomes.
CONDITIONS
Official Title
Autologous SVF Therapy for Type 2 Diabetes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 63 18 years
- Both sexes
- Diagnosis of Type 2 Diabetes Mellitus for less than 10 years
- BMI 63 25 kg/m�b2
- HbA1c between 7.5% and 9.5%
- C-peptide > 1.0 nmol/L
- Use of metformin and/or pioglitazone, with or without sulfonylurea
You will not qualify if you...
- Type 1 Diabetes Mellitus or autoimmune diabetes
- Positive anti-GAD antibodies
- Pregnancy or breastfeeding
- Use of insulin therapy
- Use of SGLT2 inhibitors
- Use of DPP-4 inhibitors
- Use of GLP-1 receptor agonists
- Unknown duration of diabetes
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Kaiser Clinica
São Jose Do Rio Preto, São Paulo, Brazil, 15.015-110
Actively Recruiting
Research Team
L
Luiz Gustavo' Quadros, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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