Actively Recruiting
Autologous Tenon's Capsule Graft for Refractory Macular Holes
Led by Benha University · Updated on 2026-01-06
20
Participants Needed
1
Research Sites
24 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This prospective interventional study evaluates the anatomical and functional outcomes of autologous Tenon's capsule grafting in patients with refractory full-thickness macular holes. Eligible patients include those with chronic large macular holes (\>400 µm) or persistent holes following prior pars plana vitrectomy with internal limiting membrane peeling and gas tamponade. Anatomical closure will be assessed using spectral-domain optical coherence tomography, and functional outcomes will be evaluated by best-corrected visual acuity over a 3-month follow-up period.
CONDITIONS
Official Title
Autologous Tenon's Capsule Graft for Refractory Macular Holes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Refractory full-thickness macular hole defined as chronic macular hole greater than 400 micrometers, or persistent macular hole following prior vitrectomy with internal limiting membrane peeling and gas tamponade
- Clear ocular media and adequate fixation for OCT imaging
- Ability to provide informed consent
You will not qualify if you...
- Active ocular infection or inflammation
- Advanced glaucoma or optic neuropathy
- History of intraocular tumors
- Severe proliferative vitreoretinopathy
- Significant systemic diseases likely to affect visual recovery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Benha University
Banhā, Benha, Egypt, 13111
Actively Recruiting
Research Team
E
Ehab Mohamed Elsayed Saad Saad, lecturer
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here