Actively Recruiting
Autologous Tumour Vaccine Trial
Led by Vaxine Pty Ltd · Updated on 2025-09-17
30
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
Sponsors
V
Vaxine Pty Ltd
Lead Sponsor
A
Australian Respiratory and Sleep Medicine Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
Phase 1 trial to evaluate the feasibility of preparation, safety, tolerability and response to a personalised autologous tumour vaccine (ATV) formulated with Advax adjuvant when administered to patients with advanced solid cancers either as monotherapy or in combination with other standard of care agents
CONDITIONS
Official Title
Autologous Tumour Vaccine Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically or cytologically confirmed advanced solid cancers or hematological cancers (lymphomas only)
- Received at least one prior therapy for this disease, unless no standard therapy options exist or patient declines standard therapies after discussion
- ECOG performance status of 2 or less
- Ability and willingness to sign informed consent (or parent if a child)
- Willingness to undergo surgery or fresh tumor biopsy if no suitable tumor tissue is available for vaccine preparation
- Agreement from primary care team to perform surgery or biopsy for tumor tissue collection
You will not qualify if you...
- Receiving any other investigational agents within the preceding 4 weeks
- Pregnant women
- No suitable cancer tissue available for vaccine preparation
- Any condition deemed by the Investigator to make the participant unsuitable for trial entry
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
ARASMI
Adelaide, South Australia, Australia, 5046
Actively Recruiting
Research Team
S
Sharen Pringle, GradCert
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here