Actively Recruiting
Led by Bakirkoy Dr. Sadi Konuk Research and Training Hospital · Updated on 2026-01-21
56
Participants Needed
1
Research Sites
17 weeks
Total Duration
Researchers are investigating the impact of automated intraoperative lung recruitment maneuvers on the occurrence of atelectasis in adult patients undergoing major laparoscopic colorectal cancer surgery. Laparoscopic colorectal surgery can increase the risk of lung collapse during and after surgery due to factors like pneumoperitoneum, patient positioning, and long anesthesia times. This trial aims to compare automated lung recruitment with standard ventilation to see if it reduces atelectasis and postoperative lung complications. Participants will be randomly assigned to one of two groups: one receiving standard mechanical ventilation without lung recruitment maneuvers, and the other receiving automated lung recruitment maneuvers delivered by the anesthesia ventilator twice during surgery. The recruitment maneuvers are applied after anesthesia induction and after stopping pneumoperitoneum. Both groups will have standardized fluid management and postoperative care. Throughout the study, lung ultrasonography will be used before, during, and after surgery to detect atelectasis and assess lung aeration. Researchers will monitor outcomes including lung ultrasound scores, postoperative pulmonary complications, hemodynamic stability, and lengths of intensive care and hospital stays. The follow-up includes assessments up to one day after surgery and monitoring for complications until hospital discharge.
CONDITIONS
Automated Intraoperative Lung Recruitment Maneuvers in Major Laparoscopic Surgery
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for eligibility assessment
Duration - Day of surgery
Participants undergo major laparoscopic colorectal surgery under general anesthesia. Those in the intervention group receive automated intraoperative lung recruitment maneuvers delivered by the anesthesia ventilator twice during surgery, while the control group receives standard mechanical ventilation without lung recruitment. Lung ultrasonography assessments are performed perioperatively to evaluate lung aeration and atelectasis.
1 intraoperative visit and 1 early postoperative visit (30 minutes after extubation)
Duration - Up to 30 days after surgery
Participants are monitored for postoperative pulmonary complications and recovery outcomes including length of intensive care unit and hospital stays. Lung ultrasonography is performed within 24 hours after surgery to assess lung aeration.
1 postoperative visit within 24 hours after surgery and additional assessments until hospital discharge
Total: 1 location
1
SBÜ Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi
Istanbul, Bakırkoy, Turkey (Türkiye), 34147
Actively Recruiting
S
Sena Gökçe Karataş
E
Evrim Kucur Tülübaş
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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