Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT07349784

Automated Intraoperative Lung Recruitment Maneuvers in Major Laparoscopic Surgery

Led by Bakirkoy Dr. Sadi Konuk Research and Training Hospital · Updated on 2026-01-21

56

Participants Needed

1

Research Sites

50 weeks

Total Duration

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AI-Summary

What this Trial Is About

Laparoscopic colorectal surgery is associated with an increased risk of intraoperative atelectasis due to pneumoperitoneum, Trendelenburg positioning, and prolonged anesthesia duration. Atelectasis developing during surgery may persist into the postoperative period and contribute to postoperative pulmonary complications. Automated lung recruitment maneuvers delivered by modern anesthesia ventilators may offer a standardized method to improve lung aeration and reduce atelectasis. This prospective, randomized, single-center controlled trial aims to evaluate the effect of automated intraoperative lung recruitment maneuvers on atelectasis detected by lung ultrasonography in patients undergoing elective major laparoscopic colorectal cancer surgery. Adult patients will be randomized to receive either automated lung recruitment maneuvers or standard mechanical ventilation without recruitment. Lung ultrasonography will be used to assess atelectasis at predefined perioperative time points. The primary outcome is the incidence of atelectasis detected by lung ultrasound, and secondary outcomes include postoperative pulmonary complications, length of intensive care unit stay, length of hospital stay, and perioperative hemodynamic instability.

CONDITIONS

Official Title

Automated Intraoperative Lung Recruitment Maneuvers in Major Laparoscopic Surgery

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 80 years
  • Scheduled for elective laparoscopic colorectal cancer surgery
  • American Society of Anesthesiologists (ASA) physical status I-III
Not Eligible

You will not qualify if you...

  • ASA physical status IV or higher
  • Pregnancy
  • Body mass index (BMI) > 40 kg/m8
  • Severe chronic obstructive pulmonary disease (COPD), GOLD stage III-IV
  • Advanced heart failure with left ventricular ejection fraction <35%
  • Previous thoracic surgery
  • Preoperative requirement for supplemental oxygen therapy
  • Refusal or inability to provide informed consent
  • Intraoperative conversion to open surgery
  • Development of significant hemodynamic instability during lung recruitment maneuvers

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

SBÜ Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi

Istanbul, Bakırkoy, Turkey (Türkiye), 34147

Actively Recruiting

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Research Team

S

Sena Gökçe Karataş

CONTACT

E

Evrim Kucur Tülübaş

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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