Actively Recruiting
Automatic Detection in MRI of Prostate Cancer: DAICAP
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2024-05-20
1250
Participants Needed
1
Research Sites
127 weeks
Total Duration
On this page
Sponsors
A
Assistance Publique - Hôpitaux de Paris
Lead Sponsor
U
University Hospital, Strasbourg, France
Collaborating Sponsor
AI-Summary
What this Trial Is About
Prostate cancer is the most common cancer in France and the 3rd most common cancer death in humans. The introduction of pre-biopsy MRI has considerably improved the quality of prostate cancer (PCa) diagnosis by increasing the detection of clinically significant PCa , and by reducing the number of unnecessary biopsies.However the diagnostic performance of Prostate MRI is highly dependent on reader experience that limits the population based delivery of high quality multiparametricMRI (mpMRI) driven PCa diagnosis. The main objective of this study is the development and the test of diagnostic accuracy of an AI algorithm for the detection of cancerous prostatic lesions from mpMRI images. The secondary objective is the development and the test of diagnostic accuracy of an AI algorithm to predict tumor aggressiveness from mpMRI images.
CONDITIONS
Official Title
Automatic Detection in MRI of Prostate Cancer: DAICAP
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male patients aged 18 years or older
- Clinical suspicion of prostate cancer based on increased PSA and/or abnormal digital rectal exam
- Diagnostic workup including multiparametric MRI and prostate biopsies following national guidelines
- For normal mpMRI (PI-RADS < 3), 12 systematic biopsy samples required
- For pathological mpMRI (PI-RADS ≥ 3), 12 systematic samples plus 2 to 4 targeted biopsy samples by cognitive or image fusion
You will not qualify if you...
- Patients with histologically confirmed prostate cancer prior to diagnostic workup
- Patients who have received treatment for prostate cancer before the study
- Patients unable to have prostate biopsies
- Patients with contraindications to performing multiparametric MRI
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
La Pitié Salpétrière Hospital
Paris, France, 75013
Actively Recruiting
Research Team
R
Raphaële Renard-Penna, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here