Actively Recruiting
Automatic Tube Compensation vs. Pressure Support Ventilation During Spontaneous Breathing Trials in Adults
Led by Rush University Medical Center · Updated on 2025-06-19
880
Participants Needed
1
Research Sites
113 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
For patients requiring mechanical ventilation, spontaneous breathing trials (SBTs) are conducted to determine if it is safe to remove the breathing tube. There are multiple methods for conducting SBTs. The purpose of this study is to compare the effects of 2 methods, pressure support ventilation (PSV) versus automatic tube compensation (ATC), on successful extubation for critically ill adult patients who received mechanical ventilation for over 24 hours.
CONDITIONS
Official Title
Automatic Tube Compensation vs. Pressure Support Ventilation During Spontaneous Breathing Trials in Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Admitted to intensive care unit (ICU)
- Age 18 years or older
- Requiring invasive mechanical ventilation for at least 24 hours
- Pass spontaneous breathing trial screen criteria
You will not qualify if you...
- Clinical decision made not to proceed with extubation regardless of spontaneous breathing trial (SBT) results
- Do not intubate (DNI) order
- Presence of tracheostomy
- Pregnancy
- Known prisoner
- Immediate need for extubation, self-extubation, or unplanned extubation that precludes safe performance of study procedures
- Enrolled in another clinical trial that impacts ventilator weaning or liberation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Rush University Medical Center
Chicago, Illinois, United States, 60612
Actively Recruiting
Research Team
J
Jie Li, PhD
CONTACT
L
Lauren Harnois, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
4
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