Actively Recruiting

Age: 50Years +
All Genders
ID06172491

Harnessing the Power of Technology to Transform Delirium Severity Measurement in the ICU

Led by Mayo Clinic · Updated on 2026-04-08

400

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying delirium severity in patients over 50 years old who are admitted to the Intensive Care Unit (ICU). This observational study aims to develop a passive digital marker (PDM) using video recordings and a trained convolutional neural network to measure delirium severity. The study also evaluates how well this digital marker compares to traditional delirium severity tools and examines its acceptance and usability by ICU nurses, patients, and caregivers. During the study, bedside cameras will record patients continuously for at least 72 hours while in the ICU, with possible extension if delirium persists and consent is given. Study staff will visit patients four times daily to ask questions about their mental, emotional health, mood, memory, and to assess alertness through voice and gentle physical prompts. Patients will also be asked to perform simple activities such as remembering and repeating words, shaking hands, and drawing objects or clocks. If a patient's alertness is lowered, observational assessments will be performed without interfering with clinical care. Participants will be monitored until discharge from the ICU. Privacy is protected by allowing coverage of cameras and blurring faces of family, clinicians, and sensitive areas before analysis. Researchers will measure delirium severity, as well as the acceptability and usability of the passive digital marker over periods ranging from 12 to 60 months. Participation is voluntary and involves detailed assessments and continuous video monitoring during ICU stay.

CONDITIONS

Brief Title

Automating Delirium Severity in the ICU

Who Can Participate

Age: 50Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age greater than 50 years
  • Expected length of stay in the ICU is more than 24 hours
  • Not admitted for acute alcohol intoxication, drug overdose, or withdrawal
Not Eligible

You will not qualify if you...

  • Admitted for acute alcohol intoxication, drug overdose, or withdrawal
  • Admitted for acute neuronal injury
  • Unable to communicate with research team due to sensory deficits (aphasic, blind, deaf) or not speaking English

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Monitoring

Duration - At least 3 days, continuing until ICU discharge if delirium persists

Participants are observed with bedside cameras for at least 72 hours, with recordings possibly continuing longer if delirium is experienced and agreed upon. The study team will visit participants 4 times daily to assess their mental and emotional health, mood, memory, and alertness through questions and activities like handshaking and drawing. Observation assessments are performed without interfering with clinical care.

4 visits daily until ICU discharge

Trial Site Locations

Total: 1 location

1

Mayo Clinic

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

H

Heidi Lindroth, PH.D. R.N.

H

Hannah Friesen

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Published Research Related To This Trial

Harnessing the Power of Technology to Transform Delirium Severity Measurement in the Intensive Care Unit: Protocol for a Prospective Cohort Study.

Roshini Raghu, Keivan Nalaie, Ivan Ayala...

https://pubmed.ncbi.nlm.nih.gov/40998312