Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05664646

Autonomic Effects of Stimulation in SCI

Led by VA Office of Research and Development · Updated on 2025-07-04

20

Participants Needed

1

Research Sites

157 weeks

Total Duration

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AI-Summary

What this Trial Is About

This study aims to determine the effects of transcutaneous spinal cord stimulation to increase blood pressure and use that device to increase power output and heart rate recovery during arm cycle ergometry. In addition, the investigators will see if the stimulation helps regulate body temperature when in a cool environment.

CONDITIONS

Official Title

Autonomic Effects of Stimulation in SCI

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Injury to the spinal cord occurred more than 1 year ago and participant is non-ambulatory
  • Level of spinal cord lesion between C3 and T6, classified as AIS A, B, or C
  • Stable prescription medication regimen for at least 30 days before enrollment
  • Ability to commit to 7 study visits within a 60-day period
Not Eligible

You will not qualify if you...

  • Extensive history of seizures
  • Dependence on a ventilator or having a patent tracheostomy site
  • History of neurologic disorders other than spinal cord injury
  • History of moderate or severe head trauma
  • Contraindications to spinal cord stimulation
  • Significant cardiovascular disease
  • Active psychological disorders
  • Substance abuse within the past 3 months
  • Open skin lesions over spine at levels targeted for stimulation (L1/L2)
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

James J. Peters VA Medical Center, Bronx, NY

The Bronx, New York, United States, 10468-3904

Actively Recruiting

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Research Team

J

Jill Wecht, EdD

CONTACT

M

Matthew T Maher, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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