Actively Recruiting
Autonomic Regulation of Blood Pressure in Premature and Early Menopausal Women
Led by University of Minnesota · Updated on 2026-01-08
160
Participants Needed
1
Research Sites
378 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a cross-sectional study in which the investigators will determine the impact of premature/early menopause on MSNA, BP and baroreflex sensitivity in younger (≤49 yr old) and older (≥50 yr old) women. Specifically, aim one will determine mechanisms driving autonomic dysregulation of BP in premature and early menopausal women and aim two will determine mechanisms driving autonomic dysregulation of BP in older menopausal women. The study design outlined below will permit testing of aim one and aim two.
CONDITIONS
Official Title
Autonomic Regulation of Blood Pressure in Premature and Early Menopausal Women
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 35-49 or 50-70 years who experienced premature (<40) or early (≤45) menopause
- Premenopausal women aged 35-49 years
- Women aged 50-70 years with typical-age menopause (after 45 years)
- Menopause confirmed by 12 months of no menstruation and serum FSH >30 mIU/mL
You will not qualify if you...
- Current nicotine or tobacco use within the past six months
- Diagnosis of diabetes or asthma
- Diagnosed significant carotid artery narrowing
- History of serious autonomic dysfunction, heart disease, respiratory disease, stroke, or severe brain injury
- Existing metabolic or endocrine disorders
- Use of heart or blood pressure medications that affect study outcomes
- Premenopausal women currently taking oral contraceptives or steroids that affect study outcomes
- Women with early or premature menopause unwilling to stop oral contraceptives or hormone therapy
- Pregnant or breastfeeding women
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Minnesota
Minneapolis, Minnesota, United States, 55455
Actively Recruiting
Research Team
M
Manda Keller-Ross, PhD, DPT, PT
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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