Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT04310644

Autonomic Small Fiber Neuropathy and Ehlers Danlos Syndromes - Prospective Study and Registry

Led by RWTH Aachen University · Updated on 2025-02-04

200

Participants Needed

1

Research Sites

521 weeks

Total Duration

On this page

Sponsors

R

RWTH Aachen University

Lead Sponsor

D

DLR German Aerospace Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

We examine patients with different autonomic neuropathies and Ehlers Danlos syndromes compared to healthy controls at three different points over time (baseline, after 3 months and after 1.5 years) to gain knowledge about the course of this disease and understand its pathophysiology, with a focus on Small Fiber neuropathy. Moreover we will validate the german version of the Malmö POTS Score and establish an easy diagnostic scheme for patients in outpatient care.

CONDITIONS

Official Title

Autonomic Small Fiber Neuropathy and Ehlers Danlos Syndromes - Prospective Study and Registry

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of autonomic neuropathy
  • Postural orthostatic tachycardia syndrome
  • Hypermobile or classical Ehlers Danlos syndromes
  • Chronic fatigue syndrome, mast cell activation syndrome, and/or PostCOVID syndrome
  • Healthy controls
  • Aged between 18 and 80 years
  • Diagnosis and clinical testing performed in the outpatient clinic for patients
  • German speaking
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Presence of a pacemaker or deep brain stimulation device
  • Sensory or motor polyneuropathy
  • Neurodegenerative disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University clinic RWTH Aachen

Aachen, North Rhine-Westphalia, Germany, 52074

Actively Recruiting

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Research Team

A

Andrea Maier, physician

CONTACT

D

Denver Igharo, student

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

5

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