Actively Recruiting
Autopsy and Photon Counting Computed Tomography to Evaluate Thromboses Related to Central Venous Catheters
Led by Thomas Kander · Updated on 2026-04-28
75
Participants Needed
1
Research Sites
176 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Central venous (CVC) is essential in modern healthcare but unfortunately associated with complications, including thrombosis. In a recently published study, it was showed that 12 out of 12 deceased patients had subclinical CVK-related thrombosis (Rockholt et al.). To shed light on this problem, the current studies were designed. In sub-study 1, deceased patients with CVC who are referred for clinical autopsy are included. Before the autopsy, the deceased will be examined with a photon-counting computed tomography (CT) scan and the results will be compared. In sub-study 2, living patients with CVC who are referred for various CT scans without contrast, are included. After informed consent, the patient will be examined with the photon-counting CT, whose reliability has been validated in Part 1 and the incidence of subclinical CVC-related thrombosis will be reported.
CONDITIONS
Official Title
Autopsy and Photon Counting Computed Tomography to Evaluate Thromboses Related to Central Venous Catheters
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diseased patients with an indwelling central venous catheter and a clinical indication for autopsy
- Informed and signed consent from next of kin (for deceased patients)
- Living patients with an indwelling central venous catheter who are referred to a CT scan without intravenous contrast
- Informed and signed consent from the patient
You will not qualify if you...
- Glomerular filtration rate (GFR) less than 15 mL/min/1.73 m2 (for living patients)
- None for deceased patients
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Intensive and Perioperative Care. Skåne University Hospital. Lund
Lund, Skåne County, Sweden, 22185
Actively Recruiting
Research Team
T
Thomas Kander, PhD
CONTACT
E
Emilia Ängeby Eriksson, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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