Actively Recruiting
Avapritinib Rollover Study
Led by Blueprint Medicines Corporation · Updated on 2026-02-09
60
Participants Needed
7
Research Sites
161 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary objective of the rollover study is to evaluate the long-term safety of avapritinib in participants who have completed a Blueprint Medicines sponsored study (parent study) and continued to benefit from avapritinib.
CONDITIONS
Official Title
Avapritinib Rollover Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participated in a Blueprint Medicines sponsored avapritinib clinical study
- Completed End of Trial / End of Study (EOT/EOS) visit in the parent study and complied with its requirements
- Continue to benefit clinically from avapritinib treatment
- Able to provide written informed consent
- Agree to continue using highly effective contraception as defined in the protocol
- Female patients of childbearing potential must have a negative highly sensitive serum pregnancy test within 20 days before the first dose; women of nonchildbearing potential do not require this test
You will not qualify if you...
- Currently participating in another interventional study
- Unwilling or unable to comply with study procedures and restrictions
- Breastfeeding
- Other protocol-defined exclusion criteria apply
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 7 locations
1
Universitair Ziekenhuis Antwerpen (UZA)
Edegem, Belgium, 2650
Actively Recruiting
2
The Hospital for Sick Children
Toronto, Ontario, Canada, M5G 1X8
Actively Recruiting
3
A.O.U. San Giovanni di Dio e Ruggi d'Aragona di Salerno
Salerno, Italy, 84131
Actively Recruiting
4
Universitair Medisch Centrum Groningen
Groningen, Netherlands, 9700
Actively Recruiting
5
Erasmus Medisch Centrum
Rotterdam, Netherlands, 3015
Actively Recruiting
6
Oslo University Hospital
Oslo, Norway, 0424
Actively Recruiting
7
Guys and St Thomas NHS Foundation Trust - St Thomas Hospital
London, United Kingdom, SE19RT
Actively Recruiting
Research Team
B
Blueprint Medicines
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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