Actively Recruiting

Phase Not Applicable
Age: 22Years +
All Genders
NCT05281237

Avecure Flexible Microwave Ablation Probe For Lung Nodules

Led by Beth Israel Deaconess Medical Center · Updated on 2026-04-08

10

Participants Needed

1

Research Sites

265 weeks

Total Duration

On this page

Sponsors

B

Beth Israel Deaconess Medical Center

Lead Sponsor

M

MedWaves, Inc

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research study to determine the effectiveness of the AveCure Flexible Microwave Ablation Probe to destroy cancerous lung nodules up to 3 c m in size. This research study involves microwave ablation (MWA)

CONDITIONS

Official Title

Avecure Flexible Microwave Ablation Probe For Lung Nodules

Who Can Participate

Age: 22Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have Stage I or II primary lung cancer with solitary nodules up to 3 cm as confirmed by pathology or rapid on-site evaluation (ROSE)
  • Have pathological proof of the target nodule's malignancy with adequate tissue sample
  • Target nodule must be accessible via navigational bronchoscopy and confirmed by cone beam CT scan during procedure
  • Must be a candidate for lung resection surgery (lobectomy or greater)
  • Be at least 22 years old and able to provide consent
Not Eligible

You will not qualify if you...

  • Cannot undergo flexible bronchoscopy
  • Target nodule is smaller than 1.0 cm
  • Have had prior radiation or neoadjuvant chemotherapy on the target nodule
  • Have any comorbidity that may affect safety or study evaluation as judged by the investigator
  • Have a pacemaker, implantable cardioverter, or other electronic implantable device
  • Cannot tolerate bronchoscopy
  • Have coagulopathy
  • Are participating in other therapeutic lung cancer studies
  • Are pregnant or breastfeeding
  • Are COVID-19 positive at the time of the procedure

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States, 02115

Actively Recruiting

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Research Team

J

Jason Beattie, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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