Actively Recruiting

Phase Not Applicable
Age: 18Years - 40Years
All Genders
Healthy Volunteers
NCT06208085

Avocado Consumption, Nutrients in Human Milk, and Infant Cognitive Development

Led by University of North Carolina, Chapel Hill · Updated on 2026-04-21

88

Participants Needed

1

Research Sites

255 weeks

Total Duration

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Sponsors

U

University of North Carolina, Chapel Hill

Lead Sponsor

A

Avocado Nutrition Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this interventional study is to establish a whole food, avocado, as a viable study material to supplement mothers and infants with nutrients that support optimal brain development. Eighty-eight breastfeeding dyads, 3m postnatal, will participate in this study designed to: 1. To document whether lactating mothers will comply in the consumption of 5 avocados a week for 12 weeks. 2. To ascertain the choline, lutein, and fatty acids present in human milk in women who eat avocado. 3. To measure the cognitive advantage conferred to infants whose mothers consume avocados while breastfeeding compared to a non-avocado-eating reference group. To this end, healthy, lactating women who are 13 weeks postpartum and their infants will be enrolled. Mothers will be provided avocados on a bi-weekly basis and will be asked to consume an avocado a day. Infant cognition will be tested when the infants are 4.5 and 6 months of age. Milk samples and diet data will be collected and assayed on a bi-weekly basis.

CONDITIONS

Official Title

Avocado Consumption, Nutrients in Human Milk, and Infant Cognitive Development

Who Can Participate

Age: 18Years - 40Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy lactating women at 13 weeks postpartum
  • Planning to exclusively breastfeed until 6 months of age
  • Gave birth at 38 weeks or greater gestation without major complications
  • Pre-pregnancy body mass index (BMI) less than 30
Not Eligible

You will not qualify if you...

  • Gestational diabetes
  • Infant with diagnosis or suspicion of developmental delay
  • Any documented seizure activity in the infant
  • Family history of avocado, latex, or banana allergies

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Nutrition Research Institute

Kannapolis, North Carolina, United States, 28081

Actively Recruiting

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Research Team

C

Carol L Cheatham, Ph.D.

CONTACT

S

Study Coordinator

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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