Actively Recruiting
AvoCog - the Effect of Daily Avocado Intake on Cognitive Function in Older Adults
Led by University of Kansas Medical Center · Updated on 2024-08-22
70
Participants Needed
1
Research Sites
85 weeks
Total Duration
On this page
Sponsors
U
University of Kansas Medical Center
Lead Sponsor
A
Avocado Nutrition Center
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to determine if adding avocados to the diet of impacts cognition in 70 older adults, age 65-85, without dementia. We will test for change in functional MRI, cognitive performance, and brain blood flow. Intervention group participants will be asked to consume 1 avocado per day for 12 weeks. Participants in the control group will be asked to continue their normal intake for 12 weeks. Throughout the study, participants will be asked to perform cognitive tests, MRI, blood tests, and questionnaires.
CONDITIONS
Official Title
AvoCog - the Effect of Daily Avocado Intake on Cognitive Function in Older Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Males and females aged 65-85 years
- Good general health with no concomitant disease
- Body mass index between 18.5 and 35 kg/m2
- Mini Mental State Exam score of 26 or higher
- Consuming 2 or fewer medium avocados per month
- Consuming 3 or more servings of carotenoid-rich foods per week and 3 or more servings of fruits and vegetables per day
- Skin carotenoid content less than 400
You will not qualify if you...
- Unwilling or unable to consume avocado
- Allergy to latex
- Taking lutein plus zeaxanthin supplements regularly
- Skin carotenoid content 400 or higher
- Central neurological diseases such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, stroke, or brain tumor
- Serious medical risks such as cancer treated by chemotherapy or radiation within the past 5 years, or recent heart attack
- Diabetes mellitus or uncontrolled high blood pressure
- Use of psychoactive or investigational medications
- Drinking 3 or more alcoholic drinks per day or substance abuse
- Unable to undergo MRI
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Kansas Medical Center
Kansas City, Kansas, United States, 66160
Actively Recruiting
Research Team
E
Emma Kelly, MS
CONTACT
M
Matthew Taylor, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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