Actively Recruiting

Phase 3
Age: 5Years - 183Months
All Genders
NCT06271174

Avoid With Locoregional Analgesia Persistant Postoperative Pain In Children

Led by Nantes University Hospital · Updated on 2024-06-12

208

Participants Needed

1

Research Sites

103 weeks

Total Duration

On this page

Sponsors

N

Nantes University Hospital

Lead Sponsor

F

Fondation Apicil

Collaborating Sponsor

AI-Summary

What this Trial Is About

Persistent postoperative pain is a substantial pain (scores 4-10 using a 0-10 numeric scale) that develops 3 months after surgery. Persistent postoperative pain can be a problem even in ambulatory surgery. Loco-regional analgesia could prevent the occurrence of this pathology but contradictory results are found in ancient studies. This study is the first randomized controlled study in children about loco-regional analgesia and persistent postoperative pain in traumatologic orthopedic surgery. One interventional arm will receive a locoregional analgesia after general anesthesia and before incision. The other arm will only receive systemic analgesia during general anesthesia. The incidence of persistent postoperative pain at 3, 6 and 12 months will be compared in these two groups. The goal is to show the decrease of the incidence of the persistent postoperative pain in the group "locoregional analgesia".

CONDITIONS

Official Title

Avoid With Locoregional Analgesia Persistant Postoperative Pain In Children

Who Can Participate

Age: 5Years - 183Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 5 years old and 15 years and 3 months
  • Traumatologic orthopedic surgery at CHU Nantes
  • Conscious patient with Glasgow score of 15
  • Able to give a verbal assessment of their pain
  • No contraindication to loco-regional analgesia
  • Member of the social security system
  • Oral consent from the patient
  • Signed consent from one parent or legal guardian
Not Eligible

You will not qualify if you...

  • Refusal to participate by patient or parent/legal guardian
  • Neurologic deficit of the operated limb before surgery
  • Ischemia of the operated limb before surgery
  • Polytraumatized patient
  • Allergy to Carbocaine
  • Atrioventricular conduction disorders
  • Participation in another analgesia study
  • Use of anticoagulant treatment
  • Uncontrolled epilepsy despite treatment
  • Porphyria

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHU Nantes

Nantes, France

Actively Recruiting

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Research Team

R

Rémi Bernardon

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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