Actively Recruiting
Baclofen for Anxiety and Alcohol Use Disorder (AUD): an Open Label Study
Led by Universitair Ziekenhuis Brussel · Updated on 2025-02-19
58
Participants Needed
1
Research Sites
269 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to determine the efficacy of baclofen for the treatment of alcohol use disorder (AUD) in patients with or without comorbid anxiety symptoms. The main questions it aims to answer are: * Do we see more abstinent days after the study period in patients with high anxiety symptoms compared to low anxiety symptoms? * Do we observe additional differences between patients with high- and low anxiety symptoms in: any drinking at the end of treatment (yes/no), number of patients who respond to treatment, anxiety score reduction, autonomic responses, craving scores, drinking motives and side effects? Participants already taking baclofen as part of routine clinical care for treatment of AUD will be asked to answer several questionnaires over a 6 week study period.
CONDITIONS
Official Title
Baclofen for Anxiety and Alcohol Use Disorder (AUD): an Open Label Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Meet DSM-5 criteria for Alcohol Use Disorder (AUD)
- Able to understand and provide written consent
- Currently receiving baclofen or started baclofen treatment at hospitalization start
- Have a desire to abstain from alcohol
You will not qualify if you...
- Have a substance use disorder other than nicotine or cannabis
- Have a significant psychiatric illness requiring medication changes within the last 30 days
- Have serious medical conditions that make baclofen use risky
- Are pregnant or breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Universitair Ziekenhuis Brussel
Jette, Brussels Capital, Belgium, 1090
Actively Recruiting
Research Team
C
Cleo L Crunelle
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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