Actively Recruiting
Bacterial Reduction for a Manual Toothbrush With a 360-Degree Mouth Cleaner Design Versus a Standard Toothbrush
Led by Colgate Palmolive · Updated on 2026-03-18
60
Participants Needed
1
Research Sites
13 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The objective of this study is to determine and compare the effectiveness of a manual toothbrush with a 360-degree mouth cleaner design versus a standard flat-trim manual toothbrush in achieving whole mouth bacterial load reduction
CONDITIONS
Official Title
Bacterial Reduction for a Manual Toothbrush With a 360-Degree Mouth Cleaner Design Versus a Standard Toothbrush
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Provide written, voluntary informed consent before any study procedures
- Be male or female aged 18 to 65 years inclusive
- Be available to complete the entire study including all visits and at-home procedures
- Be in good general and oral health as judged by the study investigator or dental examiner
- Have at least 20 permanent, natural, uncrowned teeth (not including third molars)
You will not qualify if you...
- Currently undergoing orthodontic treatment with fixed or removable appliances like braces or retainers
- Have partial removable dentures
- Have any benign or malignant tumors in the mouth, gums, palate, tongue, floor of the mouth, or jaw
- Diagnosed with moderate to advanced periodontitis as defined by clinical measures
- Have rampant or five or more active carious lesions needing immediate dental care
- Used systemic antibiotics within 30 days before screening or baseline
- Had a professional dental cleaning within 14 days before baseline
- Use prescription medications that might affect oral bacteria, saliva flow, or inflammation
- Unable or unwilling to fast (no food or drink except water) for up to 4 hours during visits
- Have a history or ongoing substance abuse affecting safety or compliance
- Are pregnant or breastfeeding at screening
- Currently use any tobacco, nicotine, or e-cigarette products
- Participated in another clinical study within 30 days that could affect results
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
M Clinical
Heredia, Costa Rica, 40101
Actively Recruiting
Research Team
M
Mauricio Monntero-Aguilar, DDS, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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