Actively Recruiting

All Genders
NCT06276543

Bactiseal Catheter Safety Registry Study

Led by Integra LifeSciences Corporation · Updated on 2025-01-27

200

Participants Needed

8

Research Sites

117 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Research Purpose: This study aims to continuously evaluate the safety of subjects implanted with a catheter (trade name: Bactiseal) produced by Integra LifeSciences Production Corporation. Device safety will be assessed based on all the adverse events that occurred within 2 years after implanted the catheter. Research Design: This study is designed to be single arm, multi-center, and retrospective. A total of 200 subjects will be retrospectively enrolled. Information will be collected on adverse events, including bacterial culture and drug resistance testing when infection (if done), of subjects enrolled within 2 years after the implantation of the Bactiseal Catheter between January 01, 2019 and June 30, 2022. The following information will be collected from subjects' medical records or hospitals' databases (if any): 1. General condition of the subjects (including previous shunting and external drainage operation) 2. Intraoperative condition and catheter implantation 3. Information on the shunt catheters 4. Adverse events of subjects within 2 years after the operation and classification of the adverse events (except anticipated adverse events listed in section 8.1.2) 5. Relevant examinations in case of postoperative infection, including bacterial culture and drug resistance testing (if done)

CONDITIONS

Official Title

Bactiseal Catheter Safety Registry Study

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • The Ethics Committee exempts informed consent or the subject or their legal representative signed the informed consent form before enrollment
  • The subject has an indication suitable for using the Bactiseal catheter
  • The subject had a hydrocephalus shunt catheter implanted for at least 2 years at enrollment
Not Eligible

You will not qualify if you...

  • The subject does not have an indication suitable for using the catheter
  • The subject is allergic to any component of the catheter, including silicone, rifampicin, or clindamycin
  • The subject had an infection at the implant site (such as ventriculitis, meningitis, peritonitis, or skin infection) when the shunt was implanted
  • The subject was implanted simultaneously with another shunt catheter different from the Bactiseal catheter
  • The subject has contraindications for shunt operation
  • The subject has uncorrected coagulopathy or any bleeding disorder

AI-Screening

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Trial Site Locations

Total: 8 locations

1

Xuanwu Hospital, Capital Medical University

Beijing, Beijing Municipality, China, 100053

Completed

2

Beijing Hospital

Beijing, Beijing Municipality, China, 100730

Completed

3

Zhujiang Hospital of Southern Medical University

Guangzhou, Guangdong, China, 510280

Completed

4

the 2nd Affiliated Hospital of Harbin Medical University

Harbin, Heilongjiang, China

Actively Recruiting

5

Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China, 430030

Completed

6

the Zhongnan Hospital of Wuhan University

Wuhan, Hubei, China, 430071

Actively Recruiting

7

Shanghai Children's Medical Center affiliated to Shanghai Jiaotong University School of Medicine

Shanghai, Shanghai Municipality, China, 200127

Actively Recruiting

8

West China Hospital of Sichuan University

Chengdu, Sichuan, China, 610041

Actively Recruiting

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Research Team

H

Hua Tang, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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