Actively Recruiting
Functional Assessment of Balance and Gait and Correlation With Kinetic and Kinematic Parameters in Patients With Multiple Sclerosis: Cross-Sectional Study
Led by University of Patras · Updated on 2026-06-05
40
Participants Needed
2
Research Sites
26 weeks
Total Duration
On this page
Sponsors
U
University of Patras
Lead Sponsor
U
University Hospital, Ioannina
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are investigating the relationship between functional measures of balance and gait and objective kinetic and kinematic parameters in people with Multiple Sclerosis (MS). This cross-sectional observational study aims to understand how biomechanical gait and balance data collected through the Vicon motion analysis system relate to clinical assessments of balance, gait, and physical performance. The study seeks to identify which biomechanical factors are most closely linked to functional abilities and mobility challenges in MS. Participants will attend a single laboratory session where they will undergo biomechanical analysis of balance and gait using the Vicon motion capture system. They will also complete standardized functional tests including the Mini Balance Evaluation Systems Test, Functional Gait Assessment, Short Physical Performance Battery, and a 2-Minute Walk Test. Additionally, they will fill out questionnaires assessing fear of falling and fatigue and have their lower-limb spasticity evaluated with the modified Ashworth Scale. During the session, which takes about 40 minutes for the primary kinetic and kinematic analysis and additional time for functional assessments, researchers will collect detailed movement data alongside clinical measures. This data will be analyzed to explore correlations between biomechanical parameters and functional outcomes. The study includes assessments of postural control, gait performance, physical endurance, fatigue, and spasticity. The findings aim to improve understanding of movement impairments in MS and support better clinical assessments and rehabilitation approaches.
CONDITIONS
Brief Title
"Balance, Gait, and Motion Analysis in Multiple Sclerosis"
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults (≥ 18 years) with confirmed diagnosis of Multiple Sclerosis
- Expanded Disability Status Scale (EDSS) score less than 6
- Ability to walk independently without assistive devices
- No significant orthopedic or neurological conditions affecting mobility
- Ability to understand and follow verbal instructions
You will not qualify if you...
- History of injury or surgery to lower limbs or spine within the past year
- Any other musculoskeletal, neurological, cardiovascular, or medical condition besides Multiple Sclerosis that affects gait, balance, or safety during testing
- Severe balance impairment or high fall risk preventing safe participation in study tasks
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey: What to Expect
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single session lasting approximately 1 hour and 15 minutes
Participants undergo a comprehensive laboratory-based assessment including biomechanical gait and balance analysis using a motion capture system, standardized clinical performance tests, and patient-reported outcome measures related to physical performance, fatigue, spasticity, and fear of falling.
1 visit (in-person)
Trial Site Locations
Total: 2 locations
1
Division of Physical Medicine and Rehabilitation/Department of Surgery, University of Ioannina Medical School
Ioannina, Greece, 45110
Actively Recruiting
2
Department of Physiotherapy of the School of Health Rehabilitation Sciences, University of Patras
Pátrai, Greece, 26504
Actively Recruiting
Research Team
E
Eirini Papakosta, PT, MSc cand.
S
Sofia Lampropoulou, PT, MSc, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here