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Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID03881930

Balance Rehabilitation With Modified Visual Input in Patients With Acquired Chronic Demyelinating Neuropathy and Proprioceptive Disorders

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-05-27

40

Participants Needed

1

Research Sites

21 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research investigates balance rehabilitation in patients with acquired chronic demyelinating neuropathy who experience walking instability due to sensitivity disorders. The study aims to evaluate how modifying visual input during rehabilitation might reduce visual dependence and strengthen proprioceptive input, potentially improving balance and walking ability in these patients. This multicenter study is conducted in the Paris area and plans to include 40 participants. Participants are randomly assigned to one of two groups. The experimental group undergoes 20 rehabilitation sessions with a Physical Therapist, performing balance exercises while keeping their eyes closed or with vision obstructed or disturbed by visual effects in a dark room. The control group also receives 20 rehabilitation sessions but performs balance exercises with their eyes open and no visual modification. Both groups have three assessments during the study. Participants will undergo evaluations including timed U-turns at comfortable and fast speeds, number of steps, double stance phase while walking, global movement amounts, walking times and steps over 10 meters, various sensory and balance tests, and balance confidence scales. Assessments occur just after rehabilitation completion and again two months later. The primary outcome is the U-turn completion time measured shortly after the last session. The rehabilitation program spans 20 sessions with follow-up evaluations up to two months post-treatment.

CONDITIONS

Brief Title

Balance Rehabilitation With Modified Visual Input in Patients With Neuropathy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with chronic demyelinating acquired neuropathy
  • Age 18 years or older
  • Able to walk 20 meters indoors without human assistance, with or without technical help
  • Complaints of discomfort or walking instability related to sensitivity disorders
  • Clinically stable for at least 2 months regardless of current treatments
  • Provided informed consent to participate
Not Eligible

You will not qualify if you...

  • Unable to walk 20 meters indoors without technical and human assistance
  • Currently hospitalized
  • Already participating in another intervention study
  • Undergoing ongoing balance rehabilitation in another center or practice
  • Started or stopped acute treatment related to polyneuropathy less than 2 months ago
  • Scheduled surgery during participation that prevents completing rehabilitation and assessments
  • Recent surgery, especially lower limb prosthesis less than 1 year old or contraindicated equipment
  • Skin wounds on the foot that prevent rehabilitation
  • Balance disorders of vestibular or central neurological origin
  • Visual disability
  • Hearing impairment preventing understanding instructions
  • Inability to speak or understand French
  • Cognitive or language impairments preventing understanding the protocol
  • Residence outside the Paris Region (Ile de France)
  • Known pregnancy
  • Not affiliated with a social security system, under guardianship, curatorship, or prisoner

Research Team

B

Bénédicte PANIGOT GUERIN, PT

A

Alain YELNIK, MD, PhD

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