Actively Recruiting
Balloon angiopLasty for Intracranial Atherosclerotic Minor Stroke/TIA
Led by Shouchun Wang, MD, PhD · Updated on 2024-01-03
416
Participants Needed
1
Research Sites
170 weeks
Total Duration
On this page
Sponsors
S
Shouchun Wang, MD, PhD
Lead Sponsor
T
The General Hospital of Northern Theater Command
Collaborating Sponsor
AI-Summary
What this Trial Is About
The objective of this study was to evaluate the safety and efficacy of early submaximal balloon angioplasty combined with medical therapy vs medical therapy alone for minor stroke/transient ischemic attack with intracranial atherosclerosis etiology.
CONDITIONS
Official Title
Balloon angiopLasty for Intracranial Atherosclerotic Minor Stroke/TIA
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 30 and 80 years
- Symptomatic intracranial atherosclerotic stenosis with 70%-99% narrowing confirmed by imaging
- Minor stroke (NIHSS score 5 or less) within 1 week of onset or worsening symptoms, or intermediate to high-risk transient ischemic attack with ABCD2 score of 4 or higher within 1 week
- Diameter of affected artery between 2.0 and 4.5 mm and stenosis length 14 mm or less
- Modified Rankin Scale score 2 or less before treatment
- No large ischemic area on CT or MRI scans (ASPECTS 6 or higher, pc-ASPECTS 8 or higher)
- Written informed consent given by the patient or legal representative
You will not qualify if you...
- Allergy to contrast media
- Non-atherosclerotic artery diseases like arterial dissection, Moya-Moya disease, or arteritis
- Lesion caused by penetrating branch occlusion on the same side as the target artery
- Severe narrowing of the extracranial artery on the side of the affected artery
- Previous endovascular treatment of the same vessel
- Presence of intracranial aneurysms, tumors, or vascular malformations
- Intracranial hemorrhage on the same side within 3 months or opposite side within 2 weeks
- Atrial fibrillation, severe heart, liver, or kidney dysfunction; serious diseases with expected survival of 1 year or less
- Low hemoglobin or platelet counts, clotting disorders, or bleeding risks
- Uncontrolled high blood pressure (systolic >185 mmHg or diastolic >110 mmHg)
- Poor blood sugar control (random glucose over 22.2 mmol/L)
- Major surgery within 30 days before enrollment or planned surgery within 90 days after
- Pregnancy or breastfeeding
- Other conditions making the patient unsuitable according to the researchers
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The First Hospital of Jilin University
Changchun, Jilin, China, 130000
Actively Recruiting
Research Team
S
Shouchun Wang, MD, PhD
CONTACT
H
Huisheng Chen, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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