Actively Recruiting
Balloon Guide Catheter to Optimize Outcomes in Stroke Thrombectomy of the Internal Carotid Artery
Led by Xuanwu Hospital, Beijing · Updated on 2025-11-17
364
Participants Needed
3
Research Sites
63 weeks
Total Duration
On this page
Sponsors
X
Xuanwu Hospital, Beijing
Lead Sponsor
F
Fujian Medical University Union Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
To investigate whether using balloon guide catheter with flow arrest during mechanical thrombectomy, compared to non-flow arrest, improves the rate of first pass expanded Thrombolysis in Cerebral Infarction score (eTICI 2c-3) reperfusion for acute ischemic stroke due to internal carotid artery occlusion
CONDITIONS
Official Title
Balloon Guide Catheter to Optimize Outcomes in Stroke Thrombectomy of the Internal Carotid Artery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Clinical diagnosis of acute ischemic stroke with internal carotid artery occlusion confirmed by imaging (CTA, MRA, or DSA), including I-type, L-type, or T-type occlusions
- Baseline NIHSS score of 6 or higher, meeting local guidelines for mechanical thrombectomy
- Time from stroke onset or last known normal to randomization within 24 hours and proceeding to mechanical thrombectomy
- Signed informed consent by the participant or legal representative
You will not qualify if you...
- Pre-stroke modified Rankin Scale (mRS) score greater than 2
- Intracranial hemorrhage visible on imaging
- Known or suspected internal carotid artery occlusion caused by dissection or atherosclerosis
- Vascular tortuosity preventing use of balloon guide catheter
- Prior stent implantation in the target vessel that would interfere with thrombectomy devices
- Any condition preventing mechanical thrombectomy
- Acute occlusion of multiple vascular territories in bilateral anterior circulation or both anterior and posterior circulations
- Pregnancy
- Allergy to contrast agents
- Refusal or inability to cooperate or tolerate interventional procedures
- Expected life expectancy less than 90 days
- Midline shift or herniation with ventricular mass effect
- Unable to participate in follow-up as assessed by investigators
- Other conditions making balloon guide catheter use unsuitable as determined by investigators
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Fujian Medical University Union Hospital
Fuzhou, Fujian, China
Actively Recruiting
2
Zhangzhou Municipal Hospital
Zhangzhou, Fujian, China
Actively Recruiting
3
Xuanwu Hospital, Capital Medical University.
Beijing, China, 100053
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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