Actively Recruiting
Barrett's Esophagus Related Neoplasia (BERN) Project
Led by Midwest Biomedical Research Foundation · Updated on 2024-11-22
150
Participants Needed
1
Research Sites
1024 weeks
Total Duration
On this page
Sponsors
M
Midwest Biomedical Research Foundation
Lead Sponsor
K
Kansas City Veteran Affairs Medical Center
Collaborating Sponsor
AI-Summary
What this Trial Is About
* The use of high resolution endoscopy (HRE), narrow band imaging (NBI) and chromoendoscopy increases the detection rates of Barrett's esophagus (BE) and early neoplasia. * Endoscopic mucosal resection (EMR) will improve the accuracy for detection of dysplasia/early neoplasia. Specific Aim 1 - To create a video-atlas of non-dysplastic and dysplastic/early neoplastic lesions in patients with BE. This will be used for training purposes and to assess learning curve associated with these new technologies. Specific Aim 2 - To create a standardized classification system for the mucosal and vascular patterns observed in patients with BE. Specific Aim 3 - To determine the interobserver agreement using the video-atlas for the mucosal and vascular patterns classification agreed upon. Specific Aim 4 - To determine the endoscopic detection rate of esophageal cancer or precancerous lesions removed during endoscopy. Specific Aim 5 - To determine the pathologic and clinical outcomes of patients undergoing EMR/ablation; including morbidity, mortality and complications of the procedure. Results to date (June 2008) : this study is active and open to enrollment. Currently 26 patients have enrolled in this study at the Kansas City VA medical center. In order to participate, patients must be eligible for care at the KCVA hospital.
CONDITIONS
Official Title
Barrett's Esophagus Related Neoplasia (BERN) Project
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 80 years
- Ability to provide written informed consent
- Referral for endoscopy to screen or monitor Barrett's esophagus or to treat early mucosal neoplasia
You will not qualify if you...
- Current use of aspirin, NSAIDs, or chronic anticoagulants that cannot be stopped before the procedure
- Unable to provide written informed consent
- Significant low platelet count or blood clotting disorder
- Any serious medical condition that prevents safe conscious sedation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Kansas city VA Medical center
Kansas City, Missouri, United States, 64128
Actively Recruiting
Research Team
A
April Higbee, BN
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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