Actively Recruiting

Phase Not Applicable
Age: 3Years - 17Years
All Genders
Healthy Volunteers
NCT05925101

Basic and Applied Research on Extinction Bursts

Led by Rutgers, The State University of New Jersey · Updated on 2026-04-29

40

Participants Needed

1

Research Sites

255 weeks

Total Duration

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AI-Summary

What this Trial Is About

Although highly effective, treatments like FCT include extinction, which can have adverse side effects. The extinction burst, an increase in the frequency or intensity of destructive behavior at the start of treatment, is the most common side effect of extinction, and can increase the risk of harm to the patient and others. The goal of the current study is to evaluate the prevalence of extinction bursts when various parameters of reinforcement (i.e., rate, magnitude, quality) are manipulated.

CONDITIONS

Official Title

Basic and Applied Research on Extinction Bursts

Who Can Participate

Age: 3Years - 17Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Children aged 3 to 17
  • Problem behavior occurring at least 10 times daily despite previous treatment
  • Problem behavior maintained by social positive reinforcement
  • Stable protective supports for self-injury with no expected changes during enrollment
  • Stable psychoactive drug regimen for at least 10 half-lives per drug or drug free
  • Stable educational plan and placement with no expected changes during treatment
Not Eligible

You will not qualify if you...

  • Currently receiving 15 or more hours per week of treatment for problem behavior
  • Diagnosis of Rett syndrome or other degenerative conditions
  • Comorbid health condition or major mental disorder interfering with participation
  • Self-injury during assessments that risks serious or permanent harm
  • Needing changes to protective supports or drug treatment during the study

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Children's Specialized Hospital-Rutgers University Center for Autism Research, Education, and Services

Somerset, New Jersey, United States, 08873

Actively Recruiting

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Research Team

W

Wayne Fisher, PhD

CONTACT

S

Serena Claiborne

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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