Actively Recruiting
BCAAs in Concussion 2.0
Led by Akiva Cohen · Updated on 2025-06-13
150
Participants Needed
1
Research Sites
69 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is a randomized, placebo-controlled, double-blinded, therapeutic exploratory clinical trial of branched chain amino acids (BCAAs) in the treatment of concussion. The aim of the study is to determine whether administration of high-dose BCAAs compared to placebo promotes concussion recovery.
CONDITIONS
Official Title
BCAAs in Concussion 2.0
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Males and females aged 11 to 23 years
- Weigh at least 40 kg
- Meet concussion criteria set by the American Congress of Rehabilitative Medicine
- Present for study within 4 days of concussion injury
- Post-menarchal females must have a negative urine pregnancy test and use acceptable contraception
- Provide informed consent; participants under 18 require parental consent and child assent
You will not qualify if you...
- Moderate or severe traumatic brain injury (GCS less than 13), hospital admission, or neurosurgical intervention
- Prior concussion or traumatic brain injury within 90 days
- Known personal or family history of maple syrup urine disease
- Use of any investigational drug within 30 days prior to enrollment
- Hypersensitivity to any ingredient in the study products
- Pregnancy, planning pregnancy during study, or breastfeeding
- Non-English speaking participants or parent/guardian
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19146
Actively Recruiting
Research Team
O
Olivia Podolak
CONTACT
M
Melissa Godfrey, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here