Actively Recruiting

Phase Not Applicable
Age: 16Years - 55Years
All Genders
NCT06829303

BCI Training for Social Cognition and Error Monitoring in ASD

Led by University of Coimbra · Updated on 2025-08-01

28

Participants Needed

1

Research Sites

91 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Social cognition seems to develop atypically in autism, particularly in processes such as faces perception, joint attention and social information processing. In this sense, and using an Emotional Paradigm of Facial Expressions (EFP) with a Brain-Computer Interface (BCI) based on Electroencephalography (EEG), the investigators intend to evaluate its effectiveness as a medical device in Autism Spectrum Disorder (ASD), namely: improving 1) social skills and 2) reducing generalized anxiety, 3) improve error monitoring, and consequently verify 4) an increase in motivation. To this end, the investigators will test a gamified intervention (EFP), using personalized feedback in real time. In this gamified interface, there is an artificial agent that learns rules through Reinforcement Learning using the evoked potentials from the participant as they observe the agent's right or wrong actions. The hypothesis is that this approach allows, during the gamified task (EFP), not only the agent/interface to learn, but also the participant through operant conditioning and implicit scrutiny of errors, which makes it particularly interesting for disorders in which error monitoring processes are compromised, as in ASD.

CONDITIONS

Official Title

BCI Training for Social Cognition and Error Monitoring in ASD

Who Can Participate

Age: 16Years - 55Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participant is able and willing to give written informed consent/assent
  • Previous diagnosis of Autism Spectrum Disorder by a qualified clinician according to gold-standard instruments
  • Aged between 16 and 55 years old
  • Normal or corrected-to-normal vision
Not Eligible

You will not qualify if you...

  • Global Intelligence Quotient <70
  • Dermatological diseases of the scalp
  • Concurrent neurofeedback therapy
  • Concomitant medication without a stable dosage for at least 4 weeks
  • History of seizures and/or epilepsy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

ICNAS

Coimbra, Portugal, 3000 548

Actively Recruiting

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Research Team

M

Miguel Castelo-Branco

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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