Actively Recruiting
BCI With Virtual Reality for Stroke Rehabilitation: A Crossover Study
Led by Technical University of Lisbon · Updated on 2026-02-03
12
Participants Needed
1
Research Sites
60 weeks
Total Duration
On this page
Sponsors
T
Technical University of Lisbon
Lead Sponsor
C
Centro de Medicina de Reabilitação de Alcoitão
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to investigate if training sessions of motor imagery associated with brain-computer interface and motor observation through virtual reality (MI-VR-BCI) can help to improve arm and hand recovery after a stroke. The main questions to answer are: * Can adding MI-BCI-VR sessions improve upper limb movement? * Can it help stroke survivors perform daily activities more easily? * Does this type of training improve brain activity and connections related to movement? Researchers will compare this type of intervention with motor imagery associated with a standard brain-computer interface intervention (MI-BCI) to see if there are added effects to upper limb function, activity and brain connections. Participants will : * Perform two intervention periods in a random order: one with MI-VR-BCI training sessions and other with MI-BCI training sessions. Each period will involve 3 weekly sessions of training, during 6 weeks, with the intervention periods being separated by 3 weeks. * Complete four assessment sessions: one at the beginning and another at the end of each intervention period.
CONDITIONS
Official Title
BCI With Virtual Reality for Stroke Rehabilitation: A Crossover Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis of stroke confirmed by neuroimaging, resulting in upper limb hemiparesis
- Time since stroke between 6 and 24 months at selection
- Sufficient cognitive ability to understand and follow intervention procedures
- Spasticity score less than 3 on the Modified Ashworth Scale in upper limb muscles
- Adults aged 18 to 80 years
- Ability to remain seated for approximately 2 hours
- Motivation to participate and ability to provide informed consent
- Undergoing conventional rehabilitation therapy during the study period
You will not qualify if you...
- Severe communication difficulties preventing understanding or following instructions
- Skin lesions, allergies, or metal implants in the head area, or history of craniectomy hindering electrode placement or EEG signal acquisition
- Other neurological or musculoskeletal conditions affecting upper limb motor function
- Neurological, musculoskeletal, or psychiatric conditions that may affect participation or outcomes (e.g., major depression, severe visual impairment, photosensitive epilepsy, frequent vertigo or dizziness)
- Upper limb impairment caused by a previous stroke
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Centro de Medicina de Reabilitação de Alcoitão
Alcabideche, Lisbon District, Portugal, 2649-506
Actively Recruiting
Research Team
A
Athanasios Vourvopoulos, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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