Actively Recruiting

Phase Not Applicable
Age: 18Years - 85Years
All Genders
NCT05872776

BEAT AF - Braking Ectopic Atrial Trends In Atrial Fibrillation

Led by Ziv HealthCare Ltd. · Updated on 2024-06-20

50

Participants Needed

2

Research Sites

106 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Paroxysmal AF subjects with a documented ECG event of AF will be recruited to the study To assess the efficacy of CardiaCare™ RR2 wearable home-care neuromodulation system in reducing AF burden and symptoms in Paroxysmal AF patients

CONDITIONS

Official Title

BEAT AF - Braking Ectopic Atrial Trends In Atrial Fibrillation

Who Can Participate

Age: 18Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Men and women ages 18-85 years with history of documented paroxysmal (<7 days) atrial fibrillation
  • AF burden between more than 0.5% and less than 25% based on continuous 14 days ECG recording
  • Ability and willingness to sign an informed consent form
  • Ability and willingness to use CardiaCare home care device and ECG chest patch with an available smartphone
  • Known symptomatic AF event within the recent 3 months
  • Willingness to not change antiarrhythmic treatment during the study
Not Eligible

You will not qualify if you...

  • Hemodynamic instability with systolic blood pressure <100mmHg or heart rate >170 bpm at baseline
  • Known history or current diagnosis of atrial flutter
  • Active myocardial infarction evident from ECG
  • Recent stroke or myocardial infarction within 6 months
  • History of sick sinus syndrome 2nd or 3rd degree AV block, bifascicular block, or prolonged (PR >300ms) 1st degree AV block
  • Unilateral or bilateral vagotomy
  • History of persistent AF with episodes lasting >7 days
  • Significant valvular disorder including prosthetic valve or hemodynamically relevant valvular diseases or valvular AF
  • History of impaired systolic function with EF <40% or NYHA Class III or IV heart failure
  • Dilated left atria with diameter >50mm on echocardiogram
  • Currently enrolled in another study
  • Recurrent vaso-vagal syncopal episodes
  • Pregnancy or breastfeeding
  • Presence of pacemaker, CRTD, or any implanted electrical stimulating device
  • History of epilepsy or seizures
  • Peripheral neuropathy or dermatological condition affecting the tested upper extremity
  • Unsuitable for study participation as determined by attending physician

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 2 locations

1

Tel Aviv Sourasky Medical Center

Tel Aviv, Israel, 64239

Actively Recruiting

2

Clalit Health Services (HMO)

Tel Aviv, Israel

Not Yet Recruiting

Loading map...

Research Team

A

Adi Benari, MSc

CONTACT

A

Amos Ziv

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here