Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
Healthy Volunteers
NCT05864521

Beetroot Juice and Sleep

Led by Mayo Clinic · Updated on 2025-09-25

60

Participants Needed

1

Research Sites

139 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to investigate the effects of acute inorganic nitrate supplementation (with beetroot) on the regulation of sleep and neurovascular physiology.

CONDITIONS

Official Title

Beetroot Juice and Sleep

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 35 years or between 65 and 80 years
Not Eligible

You will not qualify if you...

  • Coronary artery disease
  • Heart failure
  • Pregnancy
  • Diabetes
  • Sleep disorders
  • Shift work
  • Going to sleep usually after midnight
  • Travel across 2 or more time zones within one week before study visits
  • History of frequent kidney stones
  • Body mass index (BMI) of 35.0 kg/m2 or higher
  • Use of nicotine products within the past two years
  • Use of medications or supplements that affect the nitrate-nitrite-nitric oxide pathway or study outcomes, including allopurinol and proton pump inhibitors

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Mayo Clinic in Rochester

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

J

Joshua Bock, PhD

CONTACT

V

Virend Somers, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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