Actively Recruiting
Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care
Led by VA Office of Research and Development · Updated on 2026-01-09
132
Participants Needed
1
Research Sites
245 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to demonstrate whether Behavioral Activation for depression delivered via home based telehealth (BA-HT) is effective in improving social and role functioning in Veterans recently discharged from Cardiovascular disease (CVD-related) inpatient care. Eligible participants will receive either (1) twelve sessions of BA-HT or (2) standard best practices post CVD hospitalization care. Study participants will be 132 Veterans discharged from the Ralph H. Johnson VA Medical Center inpatient care facilities with CVD diagnoses corresponding to ICD 10 codes I20-I25 (120 unstable angina, stable angina; 121 NSTEMI, STEMI, initial encounter; 122 NSTEMI, STEMI, subsequent encounter; 124 acute coronary syndrome; 125 coronary arteriosclerosis with angina). They will be male or female, age 21 and above, and with approximately 40-50% minority representation. There will be assessment at baseline, 1 week post treatment, as well as 3 and 9-months post treatment. The investigators predict that BA-HT will more effectively increase social role and activity functioning, activity, mood and reduce 9-month re-hospitalization compared to current best-practices post-discharge care among patients scoring at least moderately depressed on the PROMIS Depression scale one week following hospital discharge for a CVD event.
CONDITIONS
Official Title
Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Experienced one of the following ICD 10 I20-I25 cardiovascular events or procedures in the past 6 months: unstable angina, stable angina, NSTEMI, STEMI (initial or subsequent encounter), acute coronary syndrome, coronary arteriosclerosis with angina, valve repair or replacement, Transcatheter Aortic Valve Implantation (TAVI/TAVR), pacemaker implantation, implantable cardioverter defibrillators (ICDs), left ventricular assist device, ablation therapy, or Watchman implant
- Discharged from the Ralph H. Johnson VA Medical Center inpatient care facilities
- Diagnosed with Major Depressive Disorder based on Structured Clinical Interview for DSM 5
You will not qualify if you...
- History of Coronary Artery Bypass Grafting (CABG)
- Living with a household member already enrolled in the study
- Active psychosis or significant dementia at screening
- Suicidal thoughts with clear intent
- Severe current alcohol use disorder
- Currently enrolled in another clinical trial for depression
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ralph H. Johnson VA Medical Center, Charleston, SC
Charleston, South Carolina, United States, 29401-5703
Actively Recruiting
Research Team
R
Ron E Acierno, PhD MS BA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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