Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06322420

Behavioral Activation for Depression and Habitual Rumination

Led by Ragnar Pétur Ólafsson · Updated on 2026-01-12

120

Participants Needed

1

Research Sites

155 weeks

Total Duration

On this page

Sponsors

R

Ragnar Pétur Ólafsson

Lead Sponsor

T

The Icelandic Centre for Research

Collaborating Sponsor

AI-Summary

What this Trial Is About

Depressive rumination, a negative thinking style characterized by repetitive and passive thoughts about the causes, meanings, and consequences of one's feelings and distress, is often described as being a habitual response tendency that forms a vulnerability to depression. Behavioural Activation (BA) is an effective treatment for depression but little is known of mechanisms of changes during a successful treatment completion and for whom the treatment benefits the most. The main purpose of the study is to investigate whether habit-like mood-reactive rumination will change during Behavioral Activation treatment for current depression and mediates symptom changes in the treatment. Important moderators of change will also be investigated (i.e. history of early life stress and cognitive flexibility). We aim to provide individual BA treatment for up to 120 currently depressed participants (from 90 to 120 participants) in 12 treatment sessions over 11 weeks. Measures are obtained at pre-treatment, during treatment, at post-treatment and at 6 month follow up.

CONDITIONS

Official Title

Behavioral Activation for Depression and Habitual Rumination

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Current major depressive episode diagnosed by DIAMOND interview as the primary diagnosis
  • Score of 14 or higher on Becks Depression Inventory-II for depressive symptoms in past 2 weeks
  • Age between 18 and 65 years at study start
  • Good understanding of Icelandic language to complete study measures
  • Completion of pre-treatment assessment including 2 researcher visits and 6-day ecological momentary assessment
Not Eligible

You will not qualify if you...

  • Current or past manic or hypomanic episodes diagnosed by DIAMOND interview
  • Current or past psychotic disorders diagnosed by DIAMOND interview
  • Substance abuse within the last 12 months diagnosed by DIAMOND interview
  • Active and serious suicidal thoughts or suicide attempt in the past 2 months
  • Unstable depression medication treatment in past 2 months before pre-treatment assessment
  • Recent psychotherapy in past month or ongoing psychotherapy during study
  • Cognitive impairments or severe physical illness

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of Iceland

Reykjavik, Iceland, Iceland, 102

Actively Recruiting

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Research Team

R

Ragnar P Ólafsson, PhD

CONTACT

S

Sigurður Viðar, Cand.Psych

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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