Actively Recruiting

Phase Not Applicable
Age: 55Years +
All Genders
NCT06864715

Behavioral Activation for the PreVention of Post-strokE Depression in LoW-incomE Older Stroke Survivors

Led by The University of Texas Health Science Center, Houston · Updated on 2026-04-28

350

Participants Needed

1

Research Sites

185 weeks

Total Duration

On this page

Sponsors

T

The University of Texas Health Science Center, Houston

Lead Sponsor

N

National Institute of Mental Health (NIMH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The overall objective of the project is to determine the effectiveness of tele-delivered behavioral activation (BA) by trained lay counselors (Tele-BA-S) to prevent Post-stroke depression (PSD) in low-income, older stroke survivors with subthreshold depression (SD).

CONDITIONS

Official Title

Behavioral Activation for the PreVention of Post-strokE Depression in LoW-incomE Older Stroke Survivors

Who Can Participate

Age: 55Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Enrollment within 3 months plus 2 weeks of a first-time ischemic or hemorrhagic stroke
  • 24-item Hamilton Depression Rating Scale (HDRS) score less than 15 indicating subthreshold depression
  • Single person income less than or equal to $45,000
  • Residing in a community residence
  • Ability to speak and read in English or Spanish
  • Mini-MoCA score greater than or equal to 11
Not Eligible

You will not qualify if you...

  • Stroke unrelated to vascular risk factors or transient ischemic attack
  • 24-item HDRS score 15 or higher indicating moderate to severe depression
  • Actively participating in psychotherapy
  • High suicide risk or severe psychiatric illness, or taking antipsychotics
  • Diagnosed dementia or taking cognitive enhancers, amyloid-targeting medications, or orexin receptor antagonists
  • Patient Health Questionnaire 9 score 10 or higher or positive answer to question 9
  • Diagnosed aphasia or severe cognitive impairments
  • High-risk alcohol or drug misuse
  • Taking medications for mood disorders with dose or type change in last 4 weeks

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The University of Texas Health Science Center at Houston

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

J

Jennifer Beauchamp, PhD, RN

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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