Actively Recruiting
Behavioral and Functional Task Development, Implementation, and Testing
Led by National Institute on Alcohol Abuse and Alcoholism (NIAAA) · Updated on 2026-05-07
400
Participants Needed
1
Research Sites
657 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Background: \- Scientists know that alcohol use disorders affect brain structure. They want to know more about the effects of alcohol use disorders on a person s behavior. They want to develop tasks that can be done inside a scanner that can help them better understand these effects in later studies. Objective: \- To develop tasks that investigate a person s behavior that can be used in later studies. Eligibility: * Inpatient participants of another study. They must be physically healthy right-handed adults 18-60 years old. * Healthy right-handed volunteers 18-65 years old. Design: * Participants will be screened with medical history and physical exam. They will have an EKG to record heart activity. They will give blood and urine samples and have a psychiatric interview. * Participants will have between one and three visits. * Participants will be asked about their alcohol drinking to see if they have an alcohol use disorder. * Participants will complete one of three simple computerized tasks either inside the magnetic resonance imagining (MRI) scanner or outside of it. * The MRI scanner takes pictures of the brain. The scanner is a metal cylinder. Participants lie on a table that can slide in and out of the cylinder. They will be in the scanner for about 60 minutes. They may have to lie still for up to 20 minutes. The scanner makes loud knocking noises, but they will get earplugs.
CONDITIONS
Official Title
Behavioral and Functional Task Development, Implementation, and Testing
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 65 years
- Physically healthy, right-handed adults
- Inpatient participants from another study or healthy volunteers
- Participants with alcohol dependence or moderate alcohol use disorder based on DSM criteria
You will not qualify if you...
- Not cleared on neuromotor examination
- Currently receiving psychotropic medication
- Inpatients experiencing alcohol withdrawal symptoms (CIWA score > 8) within past 30 days
- Presence of ferromagnetic objects or metal implants in the body
- Pregnant women
- Left-handed individuals
- Claustrophobia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
Research Team
B
Beth A Lee, R.N.
CONTACT
P
Paule V Joseph, C.R.N.P.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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