Actively Recruiting

Phase Not Applicable
Age: 14Years - 18Years
All Genders
NCT06765291

Behavioral Intervention for Youth to Promote Vaping Cessation

Led by Massachusetts General Hospital · Updated on 2025-10-22

400

Participants Needed

1

Research Sites

171 weeks

Total Duration

On this page

Sponsors

M

Massachusetts General Hospital

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study will test the hypothesis that the QuitVaping (QV) intervention and additional texting support will improve nicotine abstinence rates in adolescents as compared to Enhanced Usual Care (EUC: education about nicotine, vaping and addiction, advice to quit vaping, referral to TIQ texting support). Approximately 400 adolescents will be randomly assigned to one of two arms (1) QuitVaping intervention plus texting support to quit vaping and (2) EUC only.

CONDITIONS

Official Title

Behavioral Intervention for Youth to Promote Vaping Cessation

Who Can Participate

Age: 14Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 14-18 inclusive
  • Self-report of at least weekly nicotine vaping or use of other non-combusted nicotine products for at least 3 months
  • No regular use of smoked tobacco (less than 5 days per week) before enrollment and exhaled CO less than 10 ppm for those with in-person baseline visit
  • Willingness to try to quit or reduce vaping in the next 30 days
  • Ability to understand study procedures and read and write in English or Spanish
  • Have a parent or legal guardian able to participate in the opt-out process
  • Competent and willing to provide written informed consent if age 18 or assent if under 18
Not Eligible

You will not qualify if you...

  • Use of smoking cessation medications in the prior month (nicotine patch, gum, nasal spray, inhaler, varenicline, bupropion)
  • Unwillingness to abstain from using smoking cessation aids other than those provided by the study during the study period
  • Unwillingness to provide saliva or urine samples
  • Any condition or situation that would, in the investigator's opinion, make safe adherence to the study protocol unlikely

AI-Screening

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Trial Site Locations

Total: 1 location

1

Massachusetts General Hospital, Center for Addiction Medicine, 101 Merrimac Street, Suite 320, Boston, MA 02114

Boston, Massachusetts, United States, 02114

Actively Recruiting

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Research Team

A

A. Eden Evins, MD, MPH

CONTACT

J

Julia Jashinski, MSW

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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