QuitVaping and Texting Support Program to Help Teens Ages 14 to 19 Stop Vaping Nicotine

What this Trial Is About

Researchers are evaluating the QuitVaping behavioral intervention combined with additional texting support to improve nicotine abstinence rates among adolescents who vape. The study compares this approach to Enhanced Usual Care, which includes education about nicotine, vaping, addiction, advice to quit, and referral to a texting support program. Approximately 400 adolescents aged 14 to 19 who vape weekly and wish to quit or reduce vaping will participate in this randomized, double-blind trial. Participants are randomly assigned to one of two groups the QuitVaping intervention plus texting support or Enhanced Usual Care alone. QuitVaping involves 12 weekly behavioral support sessions delivered via videoconference or in person, combined with encouragement to use the This is Quitting TIQ texting program. Enhanced Usual Care participants are also encouraged to use TIQ but do not attend behavioral sessions. After the 12-week intervention, all participants have monthly follow-up visits up to week 36, conducted remotely or in person. During the study, participants attend weekly visits for assessments and behavioral sessions if assigned to QuitVaping. Researchers collect saliva samples for cotinine testing to confirm nicotine abstinence and urine samples for NNAL testing at week 12 for those reporting continuous abstinence. Assessments include vaping behavior, drug use, and medical and psychiatric evaluations. The primary outcome is continuous 4-week nicotine vaping abstinence from weeks 9 to 12, with secondary outcomes measured through week 36. Participants provide informed consent or assent according to age, with parental opt-out for younger participants.

Behavioral Intervention for Youth to Promote Vaping Cessation