Actively Recruiting
Behavioral and Neural Characteristics of Adaptive Speech Motor Control
Led by University of Washington · Updated on 2023-12-11
507
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
Sponsors
U
University of Washington
Lead Sponsor
N
National Institutes of Health (NIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study meets the NIH definition of a clinical trial, but is not a treatment study. Instead, the goal of this study is to investigate how hearing ourselves speak affects the planning and execution of speech movements. The study investigates this topic in both typical speakers and in patients with Deep Brain Stimulation (DBS) implants. The main questions it aims to answer are: * Does the way we hear our own speech while talking affect future speech movements? * Can the speech of DBS patients reveal which brain areas are involved in adjusting speech movements? Participants will read words, sentences, or series of random syllables from a computer monitor while their speech is being recorded. For some participants, an electrode cap is also used to record brain activity during these tasks. And for DBS patients, the tasks will be performed with the stimulator ON and with the stimulator OFF.
CONDITIONS
Official Title
Behavioral and Neural Characteristics of Adaptive Speech Motor Control
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Native speaker of American English
- No communication or neurological problems (except DBS group)
- Hearing thresholds equal to or better than 25 dB HL (children and young adults) or 35 dB HL (older adults) in 250-4000 Hz range
- No medications affecting sensorimotor function (except DBS group)
- Adults aged 18 years or older
- Typical children aged 4 years 0 months to 6 years 11 months or 10 years 0 months to 12 years 11 months
- Children scoring above the 20th percentile on PPVT-5, EVT-3, GFTA-3, and either TELD-4 or CELF-5 (for children 8 years or older)
- DBS patients with bilateral electrodes in ventral intermediate nucleus of thalamus or subthalamic nucleus
You will not qualify if you...
- Communication or neurological problems (except DBS group)
- Hearing thresholds worse than 25 dB HL (children and young adults) or 35 dB HL (older adults) in 250-4000 Hz range
- Use of medications affecting sensorimotor function (except DBS group)
- Not meeting age requirements for adults or typical children
- Children scoring below the 20th percentile on specified language and articulation tests
- DBS patients without bilateral electrodes in the specified brain regions
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of Washington
Seattle, Washington, United States, 98105
Actively Recruiting
Research Team
L
Ludo Max
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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