Study of How Hearing Our Own Speech Affects Speech Movement Control in Typical Speakers and Patients with Deep Brain Stimulation

What this Trial Is About

Researchers are studying how hearing our own speech influences the planning and execution of speaking movements. This study includes both typical speakers and patients with Deep Brain Stimulation DBS implants. It aims to understand whether the way we hear ourselves affects future speech and which brain areas contribute to adjusting speech movements, especially in DBS patients. The study involves manipulating real-time auditory feedback during speech using devices like digital vocal processors or software, as well as altering visual feedback during upper limb reaching movements with a virtual reality system. For DBS patients, the intervention includes switching their brain stimulator ON and OFF while performing speech tasks. These interventions help explore the role of sensory feedback and brain stimulation in speech and movement control. Participants will read words, sentences, or random syllables while their speech is recorded, and some will wear an electrode cap to record brain activity. DBS patients perform tasks with stimulator ON and OFF. Measurements include speech sounds, arm movement directions, brain electrical responses, and accuracy and timing of speech sequences. Each data session lasts from about half an hour to two hours. The study provides insight into brain and speech motor control with no treatment involved.

Behavioral and Neural Characteristics of Adaptive Speech Motor Control