Actively Recruiting

Phase Not Applicable
Age: 13Years - 30Years
All Genders
Healthy Volunteers
ID04997473

Behavioral Weight Loss Intervention Utilizing Mobile Health Technology in Hematopoietic Stem Cell Transplant Patients

Led by University of California, Los Angeles · Updated on 2026-01-28

20

Participants Needed

1

Research Sites

N/A

Total Duration

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AI-Summary

What this Trial Is About

This research aims to study obese patients aged 13 to 30 who have undergone hematopoietic stem cell transplantation (HSCT) and are at least 100 days post-transplant. The study evaluates a behavioral weight loss intervention delivered through a mobile health (mHealth) app based on addiction principles, focusing on changes in BMI, metabolic health, eating behaviors, and motivation for change. The goal is to help patients develop skills to overcome addictive eating habits and improve their health after HSCT. Participants will receive the W8L2G mobile health app along with coaching support for a total of 4 months. The intervention includes daily weekday text messages and weekly phone calls to discuss progress. Patients will be given the app and a schedule at the initial visit, then return for two additional in-clinic visits at 2 months and at the end of the 4-month program. This mobile delivery aims to provide convenience and reduce barriers such as transportation and missed school or work. Throughout the study, researchers will collect biospecimens, patient demographics, and clinical outcome data. Participants will be monitored for changes in BMI, metabolic parameters, physical activity, and addictive eating behaviors. The study involves tracking adherence to the program and assessing its feasibility. Total participation lasts about 4 months, with ongoing support and assessments conducted during clinic visits and remote contacts.

CONDITIONS

Brief Title

Behavioral Weight Loss Intervention Utilizing Mobile Health Technology in Hematopoietic Stem Cell Transplant Patients

Who Can Participate

Age: 13Years - 30Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 13 to 30 years with any type of hematopoietic stem cell transplant, at least 100 days post-transplant at initial consultation
  • Both male and female patients are eligible
  • Patients classified as obese, with a body mass index (BMI) at or above the 85th percentile for age and gender
  • Ability to read and understand English, as the app is only available in English
Not Eligible

You will not qualify if you...

  • Patients younger than 13 or older than 30 years
  • Patients less than 100 days post-transplant at initial consultation (may become eligible later if over 100 days post-transplant during enrollment window)
  • Patients whose BMI does not classify as obese
  • Patients with underlying medical conditions that significantly interfere with participation, decided on a case-by-case basis

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Screening and enrollment visit (in-person)

Outpatient Treatment

Duration - 4 months

Participants use a mobile health weight loss app based on addiction principles with coaching support for 4 months following hematopoietic stem cell transplantation.

3 in-clinic visits and weekly phone calls with daily weekday texts

Trial Site Locations

Total: 1 location

1

UCLA Mattel Children's Hospital

Los Angeles, California, United States, 90095

Actively Recruiting

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Research Team

B

Belen Ramirez

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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