Mobile Health Weight Loss Program for Obese Adolescents and Young Adults After Stem Cell Transplantation

What this Trial Is About

This research aims to study obese patients aged 13 to 30 who have undergone hematopoietic stem cell transplantation HSCT and are at least 100 days post-transplant. The study evaluates a behavioral weight loss intervention delivered through a mobile health mHealth app based on addiction principles, focusing on changes in BMI, metabolic health, eating behaviors, and motivation for change. The goal is to help patients develop skills to overcome addictive eating habits and improve their health after HSCT. Participants will receive the W8L2G mobile health app along with coaching support for a total of 4 months. The intervention includes daily weekday text messages and weekly phone calls to discuss progress. Patients will be given the app and a schedule at the initial visit, then return for two additional in-clinic visits at 2 months and at the end of the 4-month program. This mobile delivery aims to provide convenience and reduce barriers such as transportation and missed school or work. Throughout the study, researchers will collect biospecimens, patient demographics, and clinical outcome data. Participants will be monitored for changes in BMI, metabolic parameters, physical activity, and addictive eating behaviors. The study involves tracking adherence to the program and assessing its feasibility. Total participation lasts about 4 months, with ongoing support and assessments conducted during clinic visits and remote contacts.

Behavioral Weight Loss Intervention Utilizing Mobile Health Technology in Hematopoietic Stem Cell Transplant Patients