Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06061978

Benefit of Permanent Stimulation of the Left Branch of the His Bundle Versus Right Ventricular Stimulation After Atrioventricular Node Ablation for Rapid Atrial Fibrillation

Led by University Hospital, Rouen · Updated on 2026-02-10

60

Participants Needed

1

Research Sites

182 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objective of the study is to evaluate the functional benefit of left bundle branch of His pacing compared to right ventricular pacing in patients implanted with a pacemaker prior to a atrioventricular node ablation procedure for rapid atrial fibrillation

CONDITIONS

Official Title

Benefit of Permanent Stimulation of the Left Branch of the His Bundle Versus Right Ventricular Stimulation After Atrioventricular Node Ablation for Rapid Atrial Fibrillation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Pacemaker implanted patient with left bundle branch pacing lead and back-up right ventricular lead who underwent successful atrioventricular node ablation for rapid atrial fibrillation
  • Atrioventricular node ablation performed less than 15 days ago
  • Age 18 years or older
  • Women of childbearing age using effective contraception for at least 1 month and during the study, with negative pregnancy test at inclusion
  • Postmenopausal women with confirmed diagnosis (non-medically induced amenorrhea for at least 12 months prior to inclusion)
  • Membership in a social security scheme
  • Feasible patient follow-up
  • Patient has read and understood the information leaflet and signed informed consent form
Not Eligible

You will not qualify if you...

  • Impaired autonomy preventing maximal cardiorespiratory effort test (VO2 max) under good conditions (ADL scale less than 5)
  • Left ventricular ejection fraction less than 40% at inclusion
  • Person deprived of liberty by administrative or judicial decision, or under court protection, sub-guardianship or curatorship
  • Participation in another interventional trial
  • History of illness or psychological or sensory abnormality likely to prevent understanding or informed consent
  • Pregnant, parturient, or breastfeeding women, or women without proven contraception

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHU de CAEN

Caen, France

Actively Recruiting

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Research Team

C

Corentin CHAUMONT, MD

CONTACT

A

Armelle GUIDOTTI

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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Benefit of Permanent Stimulation of the Left Branch of the His Bundle Versus Right Ventricular Stimulation After Atrioventricular Node Ablation for Rapid Atrial Fibrillation | DecenTrialz